Gateway platform for biological monitoring and delivery of therapeutic compounds

• US 20060253005A1
• Filed: 04/11/2006
• Published: 11/09/2006
• Est. Priority Date: 06/29/2001
• Status: Abandoned Application

• Current Assignee: PhiloMetron Inc.
• Original Assignee: PhiloMetron Inc.
• Inventors: Drinan, Darrel D., Edman, Carl F., Merz, Diethard
• Application Number:
  US11/402,225
• Publication Number:
  US 20060253005A1
• Time in Patent Office: Days
• US Class Current: 600/300
• CPC Class Codes: A61B 2560/0271 using a remote monitoring unit
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/0022 Monitoring a patient using a global network, e.g. telephone networks, internet
• CPC Class Codes: A61B 5/02 Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/082 Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath A61B5/083, A61B5/091 take precedence
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/24 Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/486 Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61M 2005/1726 the body parameters being measured at, or proximate to, the infusion site
• CPC Class Codes: A61M 2205/3523 using telemetric means
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/13 delivered from dispensers
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: Y02A 90/10 : Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
• CPC Class Codes: Y10S 128/903 : Radio telemetry
• CPC Class Codes: Y10S 128/904 : Telephone telemetry

Abstract

The invention relates to methods and devices for remote or distributed continuous monitoring of physiologically relevant states. The invention provides for methods to automatically detect deviations or other states in physiological parameters and automatically alert a measured subject, user or other authorized party. The device provides for a universal platform for sensors, and further provides for the automatic compensation or distribution of devices or bioactive agents at appropriate levels and/or intervals in response to deviations or other states sensed in various physiological parameters.

Claims

1. A system for monitoring physiological status of a mammalian subject, comprising:

at least one biointerface head (BIH), said at least one BIH being attached to an external surface of said subject and configured to communicate data and a BIH identifier;

at least one control and communication module (CCM) storing a CCM identifier and which is linked to at least one biointerface head to receive said data and said BIH identifier, wherein said control and communication module receives data from at least one biointerface head;

at least one data collection unit (DCU) which receives data and said identifiers from the control and communication module; and

a remote database management system which receives data from at least one data collection unit and processes said data.

2. The system of claim 1, wherein said BIH comprises a device for therapeutic compound delivery.

3. The system of claim 1, wherein said BIH comprises a physiological parameter sensor.

4. The system of claim 1, wherein said biointerface head is attached to said mammalian subject with at least one adhesive.

5. The system of claim 1, wherein said control and communication module is attached to said mammalian subject with at least one adhesive.

6. The system of claim 1, wherein said system comprises a transdermal conduit and a biofluid access port, and wherein the transdermal conduit and biofluid access port are coated with a hydrogel material.

7. The system of claim 1, wherein said system further comprises a chamber which releases one or more therapeutic agents.

8. The system of claim 1, wherein said data collection unit processes information before sending information to said remote data management system.

9. The system of claim 1, wherein the data management system provides feedback to the data collection unit and/or the communication module.

10. The system of claim 1, wherein said feedback comprises diagnostic knowledge.

11. The system of claim 1, wherein said feedback comprises actions and/or instructions.

12. The system of claim 1, comprising a plurality of communication modules.

13. The system of claim 1, comprising a plurality of data collection units.

14. The system of claim 1, wherein data is transmitted from a BIH, through a plurality of CCMs, to a DCU.

15-27. -27. (canceled)