Embedded bio-sensor system
First Claim
1. A bio-sensor system adapted to provide a substantially stable voltage to a sensor assembly that is implantable in a patient such that physiological parameters thereof may be accurately measured, the bio-sensor system comprising:
- a remote transponder configured to transmit a scanner signal to the sensor and to receive a data signal therefrom;
an implantable on-chip transponder in wireless communication with the remote transponder and being configured to receive the scanner signal and transmit the data signal, the on-chip transponder including;
a sensor being configured to generate a sensor signal representative of the physiological parameter of the patient;
a power receiver configured to receive the scanner signal from the remote transponder and to generate a power signal for powering the on-chip transponder;
an analog-to-digital (A/D) assembly connected to the power receiver and the sensor, the A/D assembly being configured to respectively receive the power signal and the sensor signal and generate a digital signal in response thereto;
a data processor connected to the A/D assembly and the power receiver, the data processor being configured to respectively receive the power signal and the digital signal and generate a data signal in response thereto; and
an RF transmitter connected to the power receiver and the data processor and being configured to respectively receive the power signal and the data signal and to modulate, amplify, filter and transmit the data signal;
wherein the power receiver is configured to supply a substantially non-deviating sensor reference voltage to the sensor for accurate measurement of the physiological parameter, the remote transponder being configured to receive the data signal from the RF transmitter and to extract data representative of the physiological parameter.
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Accused Products
Abstract
Provided is a bio-sensor system which utilizes radio frequency identification technology and which includes a remote transponder in wireless communication with an implantable passively-powered on-chip transponder. The bio-sensor system is specifically adapted to provide a substantially stable and precise sensor reference voltage to a sensor assembly that is included with the on-chip transponder. The remote transponder is also configured to remotely receive data representative of a physiological parameter of the patient as well as identification data and may enable readout of one or more of the physiological parameters that are measured, processed and transmitted by the on-chip transponder upon request by the remote transponder. The precision and stability of the sensor reference voltage is enhanced by the specific circuit architecture of the glucose sensor to allow for relatively accurate measurement of the physiological parameter such as measurement of glucose concentration by a glucose sensor without the use of a microprocessor.
148 Citations
24 Claims
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1. A bio-sensor system adapted to provide a substantially stable voltage to a sensor assembly that is implantable in a patient such that physiological parameters thereof may be accurately measured, the bio-sensor system comprising:
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a remote transponder configured to transmit a scanner signal to the sensor and to receive a data signal therefrom;
an implantable on-chip transponder in wireless communication with the remote transponder and being configured to receive the scanner signal and transmit the data signal, the on-chip transponder including;
a sensor being configured to generate a sensor signal representative of the physiological parameter of the patient;
a power receiver configured to receive the scanner signal from the remote transponder and to generate a power signal for powering the on-chip transponder;
an analog-to-digital (A/D) assembly connected to the power receiver and the sensor, the A/D assembly being configured to respectively receive the power signal and the sensor signal and generate a digital signal in response thereto;
a data processor connected to the A/D assembly and the power receiver, the data processor being configured to respectively receive the power signal and the digital signal and generate a data signal in response thereto; and
an RF transmitter connected to the power receiver and the data processor and being configured to respectively receive the power signal and the data signal and to modulate, amplify, filter and transmit the data signal;
wherein the power receiver is configured to supply a substantially non-deviating sensor reference voltage to the sensor for accurate measurement of the physiological parameter, the remote transponder being configured to receive the data signal from the RF transmitter and to extract data representative of the physiological parameter. - View Dependent Claims (2, 3, 4)
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5. A bio-sensor system adapted to provide a substantially stable voltage to a sensor assembly that is implantable in a patient such that physiological parameters thereof may be accurately measured, the bio-sensor system comprising:
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a remote transponder configured to transmit a scanner signal to the sensor and to receive a data signal therefrom;
an implantable on-chip transponder in wireless communication with the remote transponder and being configured to receive the scanner signal and transmit the data signal, the on-chip transponder including;
a sensor being configured to generate a sensor signal representative of the physiological parameter of the patient;
a radio frequency (RF) receiver configured to receive the scanner signal from the remote transponder and to filter, amplify and demodulate the scanner signal and generate a message signal for controlling the on-chip transponder;
power receiver configured to receive the scanner signal from the remote transponder and to generate a power signal for powering the on-chip transponder;
analog-to-digital (A/D) assembly connected to the power receiver, the RF receiver and the sensor, the A/D assembly being configured to respectively receive the power signal, the sensor signal and the message signal and generate a digital signal in response thereto;
a data processor connected to the A/D assembly, the power receiver and the RF receiver, the data processor being configured to respectively receive the power signal, the digital signal and the message signal and generate a data signal in response thereto; and
an RF transmitter connected to the power receiver, the data processor and the RF receiver and being configured to respectively receive the power signal, the data signal and the message signal and to modulate, amplify, filter and transmit the data signal;
wherein the power receiver is configured to supply a substantially non-deviating sensor reference voltage to the sensor for accurate measurement of the physiological parameter, the remote transponder being configured to receive the data signal from the RF transmitter and to extract data representative of the physiological parameter. - View Dependent Claims (6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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22. A method of remotely monitoring physiological parameters using a bio-sensor system comprising a remote transponder and an on-chip transponder having a sensor implantable in a patient, the method comprising the steps of:
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a. remotely generating and wirelessly transmitting a scanner signal with the remote transponder, the scanner signal containing radio signal power and a telemetry data request;
b. receiving the scanner signal at the on-chip transponder and filtering, amplifying and demodulating the scanner signal to generate a message signal in response thereto;
c. collecting the radio signal power from the scanner signal and generating a power signal in response thereto;
d. sensing at least one physiological parameter of the patient at the sensor and generating an analog sensor signal in response thereto;
e. receiving the power signal, the analog sensor signal and the message signal at an analog-to-digital (A/D) assembly and generating a digital signal representative of the analog sensor signal;
f. receiving the power signal, the message signal and the digital signal at a data processor and preparing the digital signal for modulation and generating a data signal representative of the digital signal;
g. receiving the power signal, the message signal and the data signal at an RF transmitter and modulating, amplifying, filtering and wirelessly transmitting the data signal; and
h. receiving the data signal at the remote transponder and extracting data representative of the physiological parameter of the patient. - View Dependent Claims (23, 24)
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Specification