Methods and compositions for the treatment of diseases characterized by calcification and/or plaque formation
First Claim
Patent Images
1. A composition for the treatment of a disease characterized by calcification and or plaque formation comprising at least one of;
- a. a nutraceutical supplement, b. antibiotic, and c. a metal chelator.
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Accused Products
Abstract
The invention provides methods and compositions that include a nutraceutical supplement, antibiotic, and metal chelating agent that is administered to a patient to treat or prevent pathological calcification and or plaque formation as associated with Nanobacteria Calcifying Nano-Particles and/or diseases caused there-from, The method includes the administration of a therapeutically effective nutraceutical supplement, tetracycline HCL, and ethylenediaminetetraacetic acid calcium di-sodium salt to a patient in order to prevent and treat calcific disease.
17 Citations
78 Claims
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1. A composition for the treatment of a disease characterized by calcification and or plaque formation comprising at least one of;
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a. a nutraceutical supplement, b. antibiotic, and c. a metal chelator.
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2. A composition for the treatment of pathological calcification caused by Nanobacteria Calcifying Nano-Particles comprising therapeutic agents in effective amounts comprising at least one of;
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a. a nutraceutical supplement b. an antibiotic, and a c. a metal chelator. - View Dependent Claims (3, 4, 5, 8, 9, 10, 11)
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6. A composition for the treatment of pathological calcification caused by Nanobacteria Calcifying Nano-Particles comprising therapeutic agents in effective amounts comprising at least one of:
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a. a nutraceutical supplement comprising at least one of Vitamin C, Vitamin B6, Niacin, Folic Acid, Selenium, EDTA, L-Arginine, L-Lysine, L-Ornithine, Bromelain, Trypsin, CoQ10, Grapeseed Extract, Hawthorn Berry and Papain;
b. an antibiotic, and c. a metal chelator. - View Dependent Claims (12)
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7. A nutraceutical composition comprising at least one of Vitamin C, Vitamin B6, Niacin, Folic Acid, Selenium, EDTA, L-Arginine, L-Lysine, L-Ornithine, Bromelain, Trypsin, CoQ10, Grapeseed Extract, Hawthorn Berry and Papain.
- 13. A composition of nutraceutical powder comprising at least one of Vitamin C, Vitamin B6, Niacin, Folic Acid, Selenium, EDTA, L-Arginine, L-Lysine, L-Ornithine, Bromelain, Trypsin, Niacin, CoQ10, Grapeseed Extract, Hawthorn Berry and Papain in a powder form that is dispersed with water or juice and consumed by a patient in order to prevent calcification and the formation of plaque in the body as associated with nanobacteria calcifying nano-particles.
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15. A composition for the treatment of pathological calcification caused by Nanobacteria Calcifying Nano-Particles comprising therapeutic agents in effective amounts comprising at least one of:
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a. a nutraceutical supplement b. an antibiotic comprised of at least one of tetracycline, tetracycline HCL, Chlortetracycline, Democlocycline, Doxycycline, Methacycline, Oxytetracycline, Rolitetracycline, Minocycline, Sancycline, or salts thereof, and c. a metal chelator. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23)
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16. A composition for the treatment of pathological calcification caused by Nanobacteria Calcifying Nano-Particles comprising therapeutic agents in effective amounts comprising at least one of:
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a. a nutraceutical supplement b. tetracycline HCl, and c. a metal chelator.
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24. An oral dose of Tetracycline HCL in a dosage of 500 mg per day as taken by a patient in a therapeutically effective amount to stop replication of nanobacteria calcifying nano-particles in patients suffering from calcific disease or plaque.
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25. A composition for the treatment of pathological calcification caused by Nanobacteria Calcifying Nano-Particles comprising therapeutic agents in effective amounts comprising at least one of:
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a. a nutraceutical supplement;
b. an antibiotic; and
c. a metal chelator, comprising of at least one of Ethylenediaminetetraacetic acid (EDTA), Ethyleneglycoltetraacetic acid (EGTA), Diethylenetriaminepentaacetate (DTPA), Hydroxyethylethylenediaminetriacetic acid (HEEDTA), Diaminocyclohexanetetraacetic acid (CDTA), 1,2-Bis(2-aminophenoxy)ethane-N,N,N′
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-tetraacetic acid (BAPTA), and pharmaceutically acceptable salts thereof including ethylenediaminetetraacetic acid di-sodium salt or calcium di-sodium salt heavy metal sequesterant. - View Dependent Claims (26, 27, 28, 29, 30, 31, 32, 33, 34)
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- 35. Ethylenediaminetetraacetic acid calcium di-sodium salt in a daily dosage is 100-2000 mg per day per patient delivered to a patient in the form of a suppository wherein said patient applies said suppository and is instructed to lay flat and go to sleep.
- 37. A composition for the treatment of diseases characterized by pathologic calcification comprising a mixture of an antibiotic and chelating agent.
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47. An oral dispersible powder or granule, compressed pill or tablet, hard or soft capsule, suspension, lozenges, aqueous or oily suspensions, emulsions, syrup, elixir or sublingual solution comprising EDTA and Tetracycline for the treatment of Coronary Artery Disease as caused by pathologic calcification.
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48. A method for the treatment of diseases characterized by pathologic calcification comprising administering a therapeutically effective amount of a composition comprising at least one of:
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a. a nutraceutical supplement comprising at least one of Vitamin C, Vitamin B6, Niacin, Folic Acid, Selenium, EDTA, L-Arginine, L-Lysine, L-Ornithine, Bromelain, Trypsin, Niacin, CoQ10, Grapeseed Extract, Hawthorn Berry and Papain;
b. Tetracycline HCl; and
c. Ethylenediaminetetraacetic acid calcium di-sodium salt. - View Dependent Claims (49, 50, 51)
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52. A method for treating coronary artery disease caused by calcification and or plaque formation comprising administering a pharmaceutically effective amount of a composition comprising at least one of:
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a. a nutraceutical supplement comprising at least one of Vitamin C, Vitamin B6, Niacin, Folic Acid, Selenium, EDTA, L-Arginine, L-Lysine, L-Ornithine, Bromelain, Trypsin, Niacin, CoQ10, Grapeseed Extract, Hawthorn Berry and Papain;
b. Tetracycline HCL; and
c. Ethylenediaminetetraacetic acid calcium d-sodium salt. - View Dependent Claims (53, 54)
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- 55. A method for treating or preventing the growth of nanobacteria calcifying nanoparticles in vivo, comprising administering a therapeutically effective amount of a composition comprising calcium chelators, antibiotics, and nutraceutical supplements.
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59. The method of treating a disease characterized by calcification and or plaque formation comprising administering to a patient a combination comprised of at least one of:
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a. a nutraceutical supplement;
b. antibiotic; and
c. a metal chelator.
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60. A method of treating pathological calcification caused by Nanobacteria Calcifying Nano-Particles comprising administering to a patient therapeutic agents in effective amounts comprising at least one of:
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a. a nutraceutical supplement;
b. an antibiotic; and
c. a metal chelator. - View Dependent Claims (61, 62)
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63. A method of treating pathological calcification caused by Nanobacteria Calcifying Nano-Particles, comprising administering to a patient therapeutic agents in effective amounts comprising at least one of:
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a. a nutraceutical supplement;
b. an antibiotic, comprised of at least one of tetracycline, testracycline HCL, Chlortetracycline, Democlocycline, Doxycycline, Methacycline, Oxytetracycline, Rolitetracycline, Minocycline, Sancycline, or salts thereof; and
c. a metal chelator. - View Dependent Claims (64, 65, 66, 67, 68, 69)
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70. A method for the treatment of diseases characterized by pathologic calcification comprising administering a therapeutically effective amount of a composition comprising at least one of:
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a. a nutraceutical supplement comprising at least one of Vitamin C, Vitamin B6, Niacin, Folic Acid, Selenium, EDTA, L-Arginine, L-Lysine, L-Ornithine, Bromelain, Trypsin, Niacin, CoQ10, Grapeseed Extract, Hawthorn Berry and Papain;
b. Tetracycline HCl; and
c. Ethylenediaminetetraacetic acid calcium di-sodium salt. - View Dependent Claims (71, 72, 73)
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74. A method for treating coronary artery disease caused by calcification and or plaque formation comprising administering to a patient a therapeutically effective amount of at least one of:
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a. A nutraceutical supplement comprising at least one of Vitamin C, Vitamin B6, Niacin, Folic Acid, Selenium, EDTA, L-Arginine, L-Lysine, L-Ornithine, Bromelain, Trypsin, Niacin, CoQ10, Grapeseed Extract, Hawthorn Berry and Papain;
b. Tetracycline HCL; and
c. Ethylenediaminetetraacetic acid calcium d-sodium salt. - View Dependent Claims (75, 76)
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77. A composition comprising an orally administered controlled release product comprising at least one of EDTA disodium dihydrate and hydroxypropylmethylcellullose for the treatment and/or prevention of disease associated with calcification.
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78. A composition comprising of an orally administered controlled release product comprising at least one of EDTA disodium dihydrate and hydroxypropylmethylcellullose for the treatment and/or prevention of disease associated nanobacteria calcifying nanoparticles.
Specification