Removable covering for implantable frame projections
First Claim
1. A medical device for implantation in a body vessel, comprising:
- an implantable frame having a surface and a plurality of projections extending from the surface, the plurality of projections each having at least one beveled edge and including a first projection comprising a first beveled edge, the first projection having a cross-sectional area at the intersection of the projection and the surface that is less than about 10 mm2; and
a biocompatible removable material covering a first portion of the surface of the implantable frame including the first edge of the first projection.
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Accused Products
Abstract
Medical devices for implantation in a body vessel, and methods of using and making the same, are provided. A medical device can include a frame with one or more projections each having at least one edge extending from the surface of the frame, and a biocompatible, water-soluble removable material coated over at least a portion of the at least one edge. The projections can be barbs positioned to engage the interior wall of a body vessel or to attach a material, such as a valve leaflet or graft, to the frame. The removable material can be dissolved within a body vessel upon implantation, thereby exposing the at least one edge. Methods of making an implantable medical device and methods of treating a subject are also disclosed.
160 Citations
20 Claims
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1. A medical device for implantation in a body vessel, comprising:
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an implantable frame having a surface and a plurality of projections extending from the surface, the plurality of projections each having at least one beveled edge and including a first projection comprising a first beveled edge, the first projection having a cross-sectional area at the intersection of the projection and the surface that is less than about 10 mm2; and
a biocompatible removable material covering a first portion of the surface of the implantable frame including the first edge of the first projection. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. A method of treating a subject comprising the steps of:
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providing an intralumenal medical device comprising an implantable frame having a surface and a plurality of projections extending from the surface, the plurality of projections each having at least one beveled edge, the plurality of pointed projections including a first projection comprising a first beveled edge and a biocompatible and water-soluble removable material covering the first beveled edge of the first projection, the intralumenal medical device being moveable from a radially compressed to a radially expanded configuration;
introducing the intralumenal medical device within a body vessel in the radially compressed configuration;
positioning the intralumenal medical device at a point of treatment within the body vessel;
dissolving at least a portion of the water-soluble removable material within the body vessel to expose the first beveled edge of the first projection; and
radially expanding the intralumenal medical device at the point of treatment to the radially expanded configuration in a manner effective to engage the wall of the body vessel with the first beveled edge of the first projection.
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20. A method of manufacturing an implantable medical device comprising the steps of:
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providing an implantable frame having a surface having a first surface portion comprising a projection each having at least one beveled edge and a second surface portion that does not include a projection; and
applying a biocompatible water-soluble removable material to the first surface portion to cover the beveled edge of the projection, without coating the second surface portion of the implantable frame surface.
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Specification