Implantable medical device for generating cardiac pressure-volume loop and optimizing therapy
First Claim
1. An implantable medical device for generating a cardiac pressure-volume loop, the implantable medical device comprising:
- a pulse generator including control circuitry;
a first cardiac lead including a proximal end and a distal end, the cardiac lead coupled to the pulse generator at the proximal end;
a first electrode located at the distal end of the cardiac lead and operatively coupled to the control circuitry;
a sound sensor operatively coupled to the control circuitry; and
a pressure sensor operatively coupled to the control circuitry;
wherein the implantable medical device is adapted for measuring an intracardiac impedance.
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Abstract
An implantable medical device for generating a cardiac pressure-volume loop, the implantable medical device comprising a pulse generator including control circuitry, a first cardiac lead including a proximal end and a distal end and coupled to the pulse generator at the proximal end, a first electrode located at the distal end of the cardiac lead and operatively coupled to the control circuitry, a sound sensor operatively coupled to the control circuitry, and a pressure sensor operatively coupled to the control circuitry, wherein the implantable medical device is adapted for measuring intracardiac impedance. A method of using the implantable medical device to optimize therapy delivered to the heart.
78 Citations
23 Claims
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1. An implantable medical device for generating a cardiac pressure-volume loop, the implantable medical device comprising:
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a pulse generator including control circuitry;
a first cardiac lead including a proximal end and a distal end, the cardiac lead coupled to the pulse generator at the proximal end;
a first electrode located at the distal end of the cardiac lead and operatively coupled to the control circuitry;
a sound sensor operatively coupled to the control circuitry; and
a pressure sensor operatively coupled to the control circuitry;
wherein the implantable medical device is adapted for measuring an intracardiac impedance. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A method of generating a pressure-volume loop for a heart using an implantable medical device including a pulse generator, control circuitry adapted for measuring cardiac volume, a cardiac lead having a proximal end and a distal end, an electrode coupled to the distal end of the cardiac lead, a sound sensor, and a pressure sensor, the method comprising:
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creating a first corner of the pressure-volume loop by recording a first cardiac pressure and a first cardiac volume at a first time associated with an S1 heart sound;
creating a second corner of the pressure-volume loop by recording a second cardiac pressure and a second cardiac volume at a second time at which cardiac volume starts decreasing;
creating a third corner of the pressure-volume loop by recording a third cardiac pressure and a third cardiac volume at a third time associated with an S2 heart sound; and
creating a fourth corner of the pressure-volume loop by recording a fourth cardiac pressure and a fourth cardiac volume at a fourth time at which the cardiac volume increases rapidly. - View Dependent Claims (14)
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15. A method for modifying therapy delivered to a heart using an implantable medical device including a pulse generator, control circuitry adapted for measuring cardiac volume, a cardiac lead having a proximal end and a distal end, an electrode coupled to the distal end of the cardiac lead, a sound sensor, and a pressure sensor, the method comprising:
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generating a baseline pressure-volume;
storing the baseline pressure-volume loop in the control circuitry;
generating a second pressure-volume loop at a specified interval;
comparing the second pressure-volume loop to the baseline pressure-volume loop to detect a change in a cardiac parameter; and
modifying the therapy delivered to the heart in response to the change. - View Dependent Claims (16, 17, 18, 19)
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20. A method for modifying therapy delivered to a heart using an implantable medical device including a pulse generator, control circuitry adapted for measuring cardiac volume, a cardiac lead having a proximal end and a distal end, an electrode coupled to the distal end of the cardiac lead, a sound sensor, and a pressure sensor, the method comprising:
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detecting an increase in a heart rate using the electrode;
generating a first pressure-volume loop;
determining whether fibrillation is occurring based on the first pressure-volume loop; and
delivering defibrillation therapy. - View Dependent Claims (21, 22, 23)
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Specification