TRANSCUTANEOUS ANALYTE SENSOR

• US 20070208245A1
• Filed: 04/11/2007
• Published: 09/06/2007
• Est. Priority Date: 08/01/2003
• Status: Abandoned Application

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Brister, Mark, Brauker, James, Goode, Paul, Kamath, Apurv
• Application Number:
  US11/734,184
• Publication Number:
  US 20070208245A1
• Time in Patent Office: Days
• US Class Current: 600/365
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 2560/0252 using ambient temperature
• CPC Class Codes: A61B 2560/04 Constructional details of apparatus
• CPC Class Codes: A61B 2560/063 Devices specially adapted for delivering implantable medical measuring apparatus
• CPC Class Codes: A61B 2562/085 combined with means for recording calibration data
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/6833 Adhesive patches
• CPC Class Codes: A61B 5/6849 in combination with a needle set
• CPC Class Codes: A61B 5/688 using adhesives
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Claims

1. A system for monitoring a glucose concentration in a host, the system comprising:

a continuous glucose sensor configured to produce a signal indicative of a glucose concentration in a host; and

a receiver operably connected to the sensor, wherein the receiver comprises a user interface, and wherein the receiver further comprises programming configured to calibrate the signal, to display a graphical representation of the calibrated signal on the user interface, and to display a directional arrow indicative of a direction and a rate of change of the calibrated signal on the user interface.

2. The system of claim 1, wherein the receiver comprises programming configured to display the direction and the rate of change of the calibrated signal by a rotation of the directional arrow with a resolution of from about 1 degree to about 45 degrees.

3. The system of claim 1, wherein the directional arrow is indicative of a direction and a rate of change over a predetermined time period.

4. The system of claim 3, wherein the predetermined time period is at least about 15 minutes.

5. The system of claim 1, wherein the receiver comprises programming configured to display at least one of a boundary representative of an upper glucose threshold and a boundary representative of a lower glucose threshold on the user interface.

6. The system of claim 5, wherein the receiver comprises programming configured to permit a user to set the upper glucose threshold and the lower glucose threshold.

7. The system of claim 5, further comprising an alarm configured to provide at least one of a visual signal, an audible signal, and a tactile signal when the calibrated signal is below the lower glucose threshold.

8. The system of claim 5, further comprising an alarm configured to provide at least one of a visual signal, an audible signal, and a tactile signal when the calibrated signal is above the upper glucose threshold.

9. The system of claim 1, wherein the receiver comprises programming configured to estimate glucose data for a future time.

10. The system of claim 9, further comprising an alarm configured to provide at least one of a visual signal, an audible signal, and a tactile signal when the estimated glucose data for the future time is above a predetermined threshold.

11. The system of claim 9, further comprising an alarm configured to provide at least one of a visual signal, an audible signal, and a tactile signal when the estimated glucose data for the future time is below a predetermined threshold.

12. The system of claim 1, wherein the receiver further comprises a single point glucose measuring device, wherein the single point glucose measuring device is built into the receiver, and wherein the single-point glucose measuring device is configured to receive a biological sample from the host and to measure a concentration of glucose in the biological sample, wherein the measured glucose concentration in the biological sample is reference data.

13. The system of claim 12, wherein the programming configured to calibrate the signal is configured to calibrate the signal at least in part based on the reference data.

14. The system of claim 12, wherein the receiver comprises programming configured to confirm at least one of the signal and the calibrated signal at least in part based on the reference data.

15. A device comprising a computer readable memory, the computer readable memory comprising code for processing a signal from a continuous glucose measuring device, wherein the code comprises:

instructions configured to process a signal received from the continuous glucose measuring device;

instructions configured to calibrate the signal;

instructions configured to calculate a rate of change of the calibrated signal; and

instructions configured to display a graphical representation of the calibrated signal and a directional arrow indicative of a direction and a rate of change of the calibrated signal on a user interface.

16. The device of claim 15, further comprising instructions configured to display at least one of a boundary representative of an upper glucose threshold and a boundary representative of a lower glucose threshold on the user interface.

17. The device of claim 16, further comprising instructions configured allow at least one of the upper glucose threshold and the lower glucose threshold to be modified by a user.

18. The device of claim 16, further comprising instructions configured to provide an alarm comprising at least one of a visual signal, an audible signal, and a tactile signal when the calibrated signal is below the lower glucose threshold.

19. The device of claim 16, further comprising instructions configured to provide an alarm comprising at least one of a visual signal, an audible signal, and a tactile signal when the calibrated signal is above the upper glucose threshold.

20. The device of claim 15, further comprising instructions configured to estimate glucose data for a future time.

21. The device of claim 20, further comprising instructions configured to provide an alarm comprising at least one of a visual signal, an audible signal, and a tactile signal when the estimated glucose data for the future time is above a predetermined threshold.

22. The device of claim 20, further comprising instructions configured to provide an alarm comprising at least one of a visual signal, an audible signal, and a tactile signal when the estimated glucose data for the future time is below a predetermined threshold.

23. A method for displaying data from a continuous glucose measuring device, the method comprising:

generating a signal from a continuous glucose measuring device indicative of a glucose concentration in a host;

calibrating the signal; and

displaying, substantially in real-time, a graphical representation of the calibrated signal and a directional arrow indicative of a direction and a rate of change of the calibrated signal.

24. The method of claim 23, further comprising alarming the host when the calibrated signal is below a predetermined threshold, wherein the alarm comprises at least one of a visual signal, an audible signal, and a tactile signal.

25. The method of claim 23, further comprising alarming the host when the calibrated signal is above a predetermined threshold, wherein the alarm comprises at least one of a visual signal, an audible signal, and a tactile signal.

26. The method of claim 23, further comprising estimating glucose data for a future time.

27. The method of claim 26, further comprising alarming the host when the estimated glucose data for the future time is above a predetermined threshold, wherein the alarm comprises at least one of a visual signal, an audible signal, and a tactile signal.

28. The method of claim 26, further comprising alarming the host when the estimated glucose data for the future time is below a predetermined threshold, wherein the alarm comprises at least one of a visual signal, an audible signal, and a tactile signal.