Patient management system for treating depression using an implantable medical device

• US 20080027487A1
• Filed: 07/28/2006
• Published: 01/31/2008
• Est. Priority Date: 07/28/2006
• Status: Active Grant

• Current Assignee: LivaNova USA, Inc. (LivaNova Plc)
• Original Assignee: Cyberonics, Inc
• Inventors: Begnaud, Jason D., Patel, Sejal B., Rodriguez, Albert A., DuPont, Chris G.
• Granted Patent: US 8,682,445 B2
• Time in Patent Office: Days
• US Class Current: 607/2
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 1/37247 User interfaces, e.g. input or presentation means

Abstract

A method, system, graphical user interface, and apparatus are provided for performing a patient management function for treating depression using an implantable medical device. At least one patient parameter relating to an electrical signal provided by the implantable medical device for treating depression is acquired. At least one therapy parameter defining the electrical signal is correlated with at least one patient parameter. An indication relating to the correlation of the therapy parameter and the patient parameter is provided.

Claims

1. A method for managing an electrical signal therapy provided by an implantable medical device for treating depression, comprising:

acquiring at least one patient parameter relating to an electrical parameter provided by said implantable medical device for treating depression;

correlating said at least one therapy parameter defining said electrical signal with said at least one patient parameter; and

providing an indication relating to said correlation of said therapy parameter and said patient parameter.

2. The method of claim 1, wherein acquiring said patient parameter comprises acquiring data relating to a response being selected from the group consisting of a quality of life parameter, a depression score parameter, a side effect parameter, and a brain-activity parameter.

3. The method of claim 2, wherein acquiring said quality of life parameter comprises acquiring data selected from the group consisting of data relating to a patient alertness parameter, a patient verbal skills parameter, a patient mood parameter, a patient achievement parameter, a patient memory parameter. an energy level parameter, a performance parameter, a concentration level parameter, an emotional parameter, a mental overview parameter, the coordination parameter, a balance parameter, the amount of sleep parameter, and a sexual function level parameter.

4. The method of claim 2, wherein acquiring said depression score parameter comprises acquiring data selected from the group consisting of data relating to a Psychological General Well-Being Scale (PGWB), a WHO-Five Well-Being Index (WHO-5);

a Quality of Life in Depression Scale (QLDS), a Social Functioning Scale-36 (SF-36);

a Social Functioning Scale-12 (SF-12), a Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF), and a Streamlined Longitudinal Interval Continuation Evaluation-Condensed Version (SLICE-C).

5. The method of claim 1, wherein recording at least one therapy parameter comprises recording a therapy parameter selected from the group consisting of a current amplitude, a voltage amplitude, a rate of change of said current amplitude, a rate of change of said voltage amplitude, a time period of a rate of change of said current amplitude, a time period of a rate of change of said voltage amplitude, a pulse width, a rate of change of the pulse width, a time period of a rate of change of the pulse width, a frequency, a rate of change of the frequency, a time period of a rate of change of the frequency, a signal on-time, a signal off-time.

6. The method of claim 1, wherein correlating said at least one therapy parameter with said at least one physiological parameter comprises attributing a magnitude relating to at least one of a quality of life parameter, a depression score parameter, a side effect parameter, and a brain-activity parameter, to a magnitude relating to at least one of an current amplitude, a voltage amplitude, a rate of change of the amplitude, a time period of a rate of change of the amplitude, a pulse width, a rate of change of the pulse width, a time period of a rate of change of the pulse width, a frequency, a rate of change of the frequency, a time period of a rate of change of the frequency, a signal on time, a signal off time

7. The method of claim 1, wherein providing said indication comprises providing a graphical representation relating to said correlation of said therapy parameter and said physiological parameter, wherein providing said graphical representation comprises generating a graphical illustration of a trend relating to a plurality of values relating to said physiological parameter acquired over a plurality of time periods, with a plurality of values of said therapy parameter that respectively correspond to said time periods.

8. The method of claim 1, further comprising providing an interface for modifying said at least one therapy parameter based upon said indication.

9. The method of claim 8, wherein providing said interface for modifying said therapy parameter based upon said indication comprises providing a graphical user interface for inputting a value of said at least one therapy parameter.

10. The method of claim 8, wherein providing said interface for modifying said therapy parameter based upon said indication comprises providing a graphical user interface for inputting a medication and an associated dosage.

12. The graphical user interface of claim 10, wherein said display region is further adapted to display a plurality of patient data selected from the group consisting of a patient identification parameter, a date of the implant of said implantable medical device, a treatment-type parameter, a parameter relating to a lead model, and a parameter relating to a lead serial number.

13. The graphical user interface of claim 10, wherein said display region is further adapted to display a parameter screen to display a plurality of parameters selected from the group consisting of a current amplitude, a voltage amplitude, a rate of change of said current amplitude, a rate of change of said voltage amplitude, a time period of a rate of change of said current amplitude, a time period of a rate of change of said voltage amplitude, a pulse width, a rate of change of the pulse width, a time period of a rate of change of the pulse width, a frequency, a rate of change of the frequency, a time period of a rate of change of the frequency, a signal on-time, a signal off-time.

14. The graphical user interface of claim 10, wherein said display region is further adapted to display a parameter screen to display a plurality of parameters selected from the group consisting of a quality of life parameter, a depression score parameter, a side effect parameter, and a brain-activity parameter.

15. The graphical user interface of claim 13, wherein said display region is further adapted to display a plurality of said quality of life parameters selected from the group consisting of a patient alertness parameter, a patient verbal skills parameter, a patient mood parameter, a patient achievement parameter, a patient memory parameter. an energy level parameter, a performance parameter, a concentration level parameter, an emotional parameter, a mental overview parameter, the coordination parameter, a balance parameter, the amount of sleep parameter, and a sexual function level parameter.

16. The graphical user interface of claim 13, wherein said display region is further adapted to display a depression score parameter selected from the group consisting of a Psychological General Well-Being Scale (PGWB), a WHO-Five Well-Being Index (WHO-5);

a Quality of Life in Depression Scale (QLDS), a Social Functioning Scale-36 (SF-36);

a Social Functioning Scale-12 (SF-12), a Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF), and a Streamlined Longitudinal Interval Continuation Evaluation-Condensed Version (SLICE-C)

17. The graphical user interface of claim 10, wherein display region is further adapted to display a graphical illustration of a trend relating to a plurality of values relating to said physiological parameter acquired over a plurality of time periods, with a plurality of values of said therapy parameter that respectively correspond to said time periods.

18. The graphical user interface of claim 10, further comprising an interface for inputting a value of said at least one therapy parameter based upon said graphical representation

19. The graphical user interface of claim 18, wherein said interface comprises a plurality of input regions for inputting a value of said at least one therapy parameter.

20. The graphical user interface of claim 19, wherein said interface provides for automatically adjusting the value of a second parameter in response to inputting said value of said therapy parameter.

11. A graphical user interface for managing a therapy provided by a implantable medical device, comprising a display region adapted to display a visual indication of a graphical representation of a correlation between at least one patient parameter relating to an electrical signal provided by said implantable medical device for treating depression, and at least one therapy parameter defining said electrical signal delivered by said implantable medical device.

21. A computer readable program storage device encoded with instructions that, when executed by a computer, performs a method for managing an electrical signal therapy provided by a implantable medical device for treating depression, the method comprising:

acquiring at least one patient parameter relating to an electrical parameter provided by said implantable medical device for treating depression;

correlating said at least one therapy parameter defining said electrical signal with said at least one patient parameter; and

providing an indication relating to said correlation of said therapy parameter and said patient parameter.