System for perfusion management

• US 20080058713A1
• Filed: 08/09/2007
• Published: 03/06/2008
• Est. Priority Date: 04/19/2004
• Status: Active Grant

• Current Assignee: Gearbox LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Wood, Lowell
• Granted Patent: US 7,879,023 B2
• Time in Patent Office: Days
• US Class Current: 604/67
• CPC Class Codes: A61B 1/00016 using wireless means
• CPC Class Codes: A61B 1/041 Capsule endoscopes for imaging
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/24 with a catheter A61B18/26, A61B18/28 take precedence
• CPC Class Codes: A61B 2562/028 Microscale sensors, e.g. electromechanical sensors [MEMS]
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/076 Permanent implantations telemetry using implanted circuitry A61B5/0031; implanted stimulators for therapy A61N1/3605, A61N1/362, A61N1/372
• CPC Class Codes: A61B 5/145 Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissuemeasuring of blood pressure or blood flow A61B5/02; non-radiation detecting or locating of foreign bodies in blood A61B5/06
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/6876 Blood vessel
• CPC Class Codes: A61B 5/7232 involving compression of the physiological signal, e.g. to extend the signal recording period
• CPC Class Codes: A61M 1/77 Suction-irrigation systems aspiration tips supplying fluids A61M1/85; specific for negative pressure wound therapy A61M1/92; combined with tracheal tubes A61M16/0463
• CPC Class Codes: A61M 2205/05 combined with other kinds of therapy
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 2205/3592 using telemetric means, e.g. radio or optical transmission
• CPC Class Codes: A61M 2209/01 Remote controllers for specific apparatus
• CPC Class Codes: A61M 2209/084 Supporting bases, stands for equipment
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16827 : controlling delivery of multiple fluids, e.g. sequencing, mixing or via separate flow-paths infusion of multiple fluids without using a controller A61M5/1407
• CPC Class Codes: A61M 5/1723 : using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies.

Claims

1-37. -37. (canceled)

38. A method for making a device, comprising:

providing a cavity for storing a receivable; and

including at least one transmitting channel coupled to said cavity for delivering said receivable from said cavity to a predetermined location in an animal, cooperative with a monitoring system and a detecting system including logic and/or software operative for delivering said receivable.

39. The method according to claim 38, comprising the step of transferring a fluid to said cavity.

40. The method according to claim 39, wherein said device includes a pump, and/or a source of pressure, coupled to said cavity for transferring said fluid.

41. The method according to claim 38, comprising the step of coupling a motor and/or an actuator to said at least one transmitting channel.

42. The method according to claim 38, comprising the step of configuring said device to be monitored and/or controlled by a person.

43. The method according to claim 38, comprising the step of configuring said device for implantation in said predetermined location in said animal.

44. The method according to claim 38, further comprising the step of coupling said cavity to a mixing cavity.

45. The method according to claim 38, further comprising the step of coupling a source of an electric charge, and/or an electromagnetic radiation, to said at least one transmitting channel.

46. The method according to claim 38, including coupling a source of a chemical, a chemical compound, a protein, a lipoprotein, a glycoprotein, a sugar, a lipid, an antigen, an antibody, a cytokine, a peptide, a neurotransmitter, a hormone, an ion, a messenger molecule, a nucleic acid, an engineered nucleic acid, a nucleic acid vector, a drug, a cell, a cell fragment, a cell organelle, a liposome, a pharmaceutical agent, a biological material, and/or a biological fraction internal and/or external to said cavity.

47. The method according to claim 38, including coupling a source of two or more of a chemical, a chemical compound, a protein, a lipoprotein, a glycoprotein, a sugar, a lipid, an antigen, an antibody, a cytokine, a peptide, a neurotransmitter, a hormone, an ion, a messenger molecule, a nucleic acid, an engineered nucleic acid, a nucleic acid vector, a drug, a cell, a cell fragment, a cell organelle, a liposome, a pharmaceutical agent, a biological material, and/or a biological fraction internal and/or external to said cavity.

48. The method according to claim 38, including coupling a device for data gathering, processing, storage and/or transmission to said monitoring system and/or said detecting system.

49. The method according to claim 38, wherein said monitoring system communicates wirelessly.

50. The method according to claim 38, wherein said monitoring system is operative for guiding and/or extending and/or moving said transmitting channel.

51. The method according to claim 38, wherein said monitoring system comprises a processor, a feedback circuit, and/or a logic circuit.

52. The method according to claim 38, wherein said monitoring system is a processor further comprising a stored software and/or firmware program cooperative with said processor.

53. The method according to claim 38, wherein said transmitting channel is formed from a plurality of extending parts.

54. The method according to claim 53, wherein said plurality of extending parts includes portions that are hollow.

55. The method according to claim 38, comprising the step of coupling a flow regulator and/or a flow monitor to said transmitting channel and/or said receptacle.

56. The method according to claim 38, comprising the step of coupling a device for partially blocking and/or shunting a liquid flow to said transmitting channel.

57. The method according to claim 38, comprising the step of coupling an operative tool to said at least one transmitting channel.

58. The method according to claim 57, wherein said operative tool comprises a positioning tool, an imaging device, a device for ablating, and/or degrading and/or liquefying a cell, a mass of cells, a tissue, a colloid, an emulsion, and/or an assembly of biological materials exhibiting shear strength.

59. The method according to claim 38, comprising the step of coupling a vacuum, a siphon, and/or an evacuation device to said at least one transmitting channel.

60. The method according to claim 38, comprising coupling a device for cauterizing and/or sealing a cell, a mass of cells, a tissue, an organ, an assembly of biological materials exhibiting shear strength, and/or a structure to said at least one transmitting channel.

61. The method according to claim 38, comprising the step of coupling a stent to said at least one transmitting channel.

62. The method according to claim 38, further including coupling a dispenser to said transmitting channel, said dispenser including a fluid controller operative to provide a fluid at a controlled rate.

63. The method according to claim 38, further including coating said at least one transmitting channel with a polymer and/or a biocompatible material.

64. The method according to claim 38, wherein said detecting system includes coupling an imager, a pressure sensor, a temperature sensor, a chemical sensor, a gas sensor, an electrolyte sensor, a concentration sensor, a composition sensor, and/or a flow sensor coupled to said at least one transmitting channel.

65-84. -84. (canceled)