Silicon microprobe with integrated biosensor
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Abstract
Microprobe device 10 provides an analyte signal from biosensor 12 to an external analyte meter indicating analyte presence in an analyte-containing bodily fluid of a subject (not shown).
203 Citations
46 Claims
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1-25. -25. (canceled)
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26. A microprobe device comprising:
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a substrate comprising a body, and a microprobe having a body end connected to the body and a penetration end terminating in a point configured to make an incision in the stratum corneum, the penetration end extending along the microprobe from a location recessed from any area of tip formation to the termination of the microprobe and being completely uncovered, any change in overall microprobe thickness along an entire length of the penetration end having a smooth transition; and
one or more sensors non-displaceably adhered to the substrate and located away from the penetration end, such that no sensors are located in any part of the penetration end. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41)
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42. A microprobe device comprising:
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a substrate comprising a body and a microprobe having a body end connected to the body and a penetration end;
an open fluid channel formed in the substrate, the channel opening along a surface of the substrate; and
a sensor located on the substrate, wherein at least part of the sensor is positioned to pass uncovered into a subject during use. - View Dependent Claims (43, 44, 45, 46)
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Specification