PHARMACEUTICAL COMPOSITIONS COMPRISING A BISPHOSPHONATE COMPOUND

  • US 20080167271A1
  • Filed: 11/16/2007
  • Published: 07/10/2008
  • Est. Priority Date: 11/17/2006
  • Status: Abandoned Application
First Claim
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1. A pharmaceutical composition comprising:

  • (i) a therapeutically effective amount of at least one bisphosphonate,(ii) a non-irritating amount of at least one moisturizer,(iii) at most 0-12% of a short-chain aliphatic alcohol selected from the group consisting of ethanol, n-propanol, isopropanol, n-butanol, tert-butanol, isobutanol and mixtures thereof,(iv) at least one gelling agent,(v) optionally, at least one surfactant, and(vi) water,wherein said compositionis a stable, macroscopically homogeneous mixture,has a pH of between 4.0 and 8.5, andis non-occlusive and non film-forming.

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