TRANSCUTANEOUS ANALYTE SENSOR

• US 20080194935A1
• Filed: 04/11/2008
• Published: 08/14/2008
• Est. Priority Date: 07/13/2004
• Status: Active Grant

Abstract

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Claims

1. A sensor system for measuring an analyte concentration in a host, the sensor system comprising:

a sensor comprising at least one electrode; and

sensor electronics configured to measure the analyte concentration in the host when the sensor is implanted therein, wherein the sensor electronics comprise a data sampling portion in data communication with the at least one electrode, wherein the data sampling portion comprises an analog portion configured to measure the current flowing at the at least one electrode and to convert the current measurement to digital values representative of the current, wherein the digital values are acquired at a predetermined time interval, and wherein the predetermined time interval is programmed to be programmable after the sensor electronics have been manufactured.

2. The sensor system of claim 1, wherein the predetermined time interval is programmable at an interval from about 2 seconds to about 512 seconds.

3. The sensor system of claim 1, wherein the sensor electronics comprise a transmitter portion for transmitting a signal indicating a level of the analyte in the host at a programmable transmission interval, wherein the programmable transmission interval is a multiple of the predetermined time interval.

4. The system of claim 3, wherein the transmission interval is programmable from about 2 seconds to about 850 minutes.

5. The system of claim 1, wherein the sensor electronics are configured to measure the current flow in at least a picoAmp range.

6. The system of claim 1, wherein the sensor electronics comprise an ASIC, wherein the ASIC comprises the data sampling portion.

7. The system of claim 1, wherein the data sampling portion comprises a current-to-frequency converter.

8. The system of claim 1, further comprising a digital filter configured to smooth the digital values.

9. The system of claim 1, wherein the sensor electronics further comprise a transmitter portion configured to build and transmit a data packet, wherein the data packet comprises a plurality of bits, wherein at least some of the plurality of bits include at least one digital value representative of the current.

10. The system of claim 9, wherein the at least one digital value comprises a filtered digital value.

11. The system of claim 9, wherein the at least some of the plurality of bits further include sensor identification information.

12. The system of claim 9, wherein the at least some of the plurality of bits further include error detection.

13. The system of claim 9, wherein the at least some of the plurality of bits further include error correction.

14. The system of claim 1, further comprising a transmitter portion configured to build and transmit a data packet, wherein the data packet comprises a plurality of bits, wherein at least some of the plurality of bits include at least one digital value representative of the current, wherein the at least some of the plurality of bits further include sensor identification information.

15. The system of claim 1, further comprising a transmitter portion configured to build and transmit a data packet, wherein the data packet comprises a plurality of bits, wherein at least some of the plurality of bits include at least one digital value representative of the current, wherein the at least some of the plurality of bits further include error detection.

16. The system of claim 1, further comprising a transmitter portion configured to build and transmit a data packet, wherein the data packet comprises a plurality of bits, wherein at least some of the plurality of bits include at least one digital value representative of the current, wherein the at least some of the plurality of bits further include error correction.

17. The system of claim 1, further configured to verify the identification information encoded with the data packet.

18. The system of claim 1, further comprising a receiver configured to perform error correction on the received data packet.

19. The system of claim 1, wherein the sensor further configured to detect one or more glucose data points.

20. The system of claim 1, wherein the sensor is physically electrically contacted with the sensor electronics.

21. The system of claim 1, further comprising a receiver configured to determine glucose information corresponding to the sensor signal, and wherein the receiver is configured to output the glucose information.

22. The system of claim 1, further comprising a receiver operatively coupled to the sensor electronics configured to receive transmitted signals corresponding to the analyte concentration.

23. The system of claim 22, wherein the receiver is configured to decode the encoded signals received from the transmitter.

24. The system of claim 23, wherein the receiver is configured to perform non-iterative decoding techniques on the signals.

25. The system of claim 23, wherein the receiver is configured to perform iterative decoding techniques on the signals.

26. The system of claim 22, wherein the receiver performs a Cyclic Redundancy Check to verify data integrity upon receipt of the transmitted signals.

27. The system of claim 1, wherein the sensor electronics further comprise a transmitter portion configured to build and transmit a data packet, wherein the data packet comprises a plurality of bits, wherein at least some of the plurality of bits include at least one of a sensor ID code, status code and a calibration code.

28. A continuous glucose monitoring system, comprising:

a sensor configured to detect a current flow associated with one or more glucose levels;

sensor electronics operatively coupled to the sensor, the sensor electronics configured to receive the one or more glucose levels and to transmit signals corresponding to the one or more glucose levels; and

a receiver in operative communication with the sensor electronics configured to receive transmitted signals corresponding to the detected one or more glucose levels, wherein the sensor electronics are configured to detect a current drop to zero in the working electrode associated with removal of a sensor from the host.