SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA

• US 20080195967A1
• Filed: 04/14/2008
• Published: 08/14/2008
• Est. Priority Date: 08/01/2003
• Status: Active Grant

• Current Assignee: DexCom Incorporated
• Original Assignee: DexCom Incorporated
• Inventors: Brauker, James H., Carr-Brendel, Victoria, Goode, Paul V., Kamath, Apurv U.
• Granted Patent: US 7,583,990 B2
• Time in Patent Office: Days
• US Class Current: 715/781
• CPC Class Codes: A61B 2560/0223 of calibration, e.g. protocols for calibrating sensors
• CPC Class Codes: A61B 2560/04 Constructional details of apparatus
• CPC Class Codes: A61B 2562/085 combined with means for recording calibration data
• CPC Class Codes: A61B 3/10 Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
• CPC Class Codes: A61B 5/0031 Implanted circuitry
• CPC Class Codes: A61B 5/1433 provided with locking means details of syringes A61M5/315
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/1468 using chemical or electrochemical methods, e.g. by polarographic means A61B5/1486 takes precedence
• CPC Class Codes: A61B 5/1473 invasive, e.g. introduced into the body by a catheter A61B5/1482 takes precedence
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/743 Displaying an image simultaneously with additional graphical information, e.g. symbols, charts, function plots
• CPC Class Codes: G01N 33/48707 by electrical means G01N33/49, G01N33/493 take precedence
• CPC Class Codes: Y02A 90/10 Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Abstract

Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Claims

1. A system for displaying data from a continuous glucose sensor, the system comprising:

a sensor data receiving module that receives sensor data including one or more sensor data points from the substantially continuous glucose sensor; and

an interface control module that displays sensor data on a user interface responsive to a level of stability of the sensor data.

2. The system of claim 1, wherein the interface control module is configured to display sensor data only after a predetermined level of stability has been determined.

3. The system of claim 1, wherein the interface control module is configured to alter the user interface based on the level of stability of the sensor data.

4. The system of claim 1, wherein the interface control module is configured to provide an indication of the level of stability of the sensor data.

5. The system of claim 4, wherein the indication comprises flashing information and/or faded information on the user interface.

6. The system of claim 1, wherein the interface control module is configured to display sensor data in a display format comprising a numeric glucose value, a directional trend of glucose data, and/or a graphical representation of glucose data.

7. The system of claim 6, wherein the interface control module is configured to selectively alter the display format based on the level of stability of the sensor data.

9. The method of claim 1, wherein displaying sensor data on a user interface responsive to a level of stability of the sensor data comprises displaying sensor data only after a predetermined level of stability has been determined.

10. The method of claim 1, wherein the interface control module is configured to alter the user interface based on the level of stability of the sensor data.

11. The method of claim 1, further comprising providing an indication of the level of stability of the sensor data.

12. The method of claim 11, wherein the indication comprises flashing information and/or faded information on the user interface.

13. The method of claim 1, wherein displaying sensor data on a user interface responsive to a level of stability of the sensor data comprises displaying the sensor data in a display format comprising a numeric glucose value, a directional trend of glucose data, and/or a graphical representation of glucose data.

14. The method of claim 13, further comprising selectively altering the display format based on the level of stability of the sensor data.

8. A method for displaying data from a continuous glucose sensor, the method comprising:

receiving sensor data including one or more sensor data points from the substantially continuous glucose sensor; and

displaying sensor data on a user interface responsive to a level of stability of the sensor data.

15. A continuous glucose sensor system, comprising:

a continuous glucose sensor configured to continuously measure a concentration of glucose in a host; and

a computer system configured to receive sensor data associated with the concentration of glucose in the host and configured to process the sensor data to provide displayable sensor data, wherein the computer system is configured to display sensor data on a user interface responsive to a level of stability of the sensor data.

16. The system of claim 15, wherein the computer system is configured display the sensor data on the user interface only when a predetermined level of stability of the continuous glucose sensor is determined.