8-Substituted Benzoazepines as Toll-Like Receptor Modulators
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Abstract
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in the treatment of autoimmunity, inflammation allergy, asthma, graft rejection, graft versus host disease, infection, sepsis, cancer and immunodeficiency.
62 Citations
23 Claims
- 1. A compound of the Formula
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20-21. -21. (canceled)
Specification