Controllable release nasal system

• US 20080243056A1
• Filed: 03/11/2008
• Published: 10/02/2008
• Est. Priority Date: 04/12/2006
• Status: Abandoned Application

• Current Assignee: Searete LLC (Intellectual Ventures LLC)
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Ishikawa, Muriel Y., Tegreene, Clarence T., Hillis, W. Daniel, Hyde, Roderick A., Sweeney, Elizabeth A., Wood, Victoria Y.H., Wood, Lowell L., Wilson, Richa
• Application Number:
  US12/075,480
• Publication Number:
  US 20080243056A1
• Time in Patent Office: Days
• US Class Current: 604/66
• CPC Class Codes: A61B 2562/17 Comprising radiolucent components
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/418 lymph vessels, ducts or nodes
• CPC Class Codes: A61K 9/0043 Nose
• CPC Class Codes: A61M 15/08 Inhaling devices inserted into the nose
• CPC Class Codes: A61M 15/085 Fixing means therefor
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/3306 Optical measuring means
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2230/005 Parameter used as control input for the apparatus
• CPC Class Codes: A61M 2230/06 Heartbeat rate only
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 2230/30 Blood pressure A61M2230/04 takes precedence
• CPC Class Codes: A61M 2230/50 Temperature
• CPC Class Codes: A61M 31/00 Devices for introducing or retaining media, e.g. remedies, in cavities of the body A61M25/00 takes precedence ; introducing or retaining ophthalmic products into the ocular cavities A61F9/0008

Abstract

Embodiments of devices and system for controllable nasal delivery of materials are described. Methods of use of such devices and system and software for controlling the operation of such devices and systems are also disclosed.

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100. A signal bearing medium comprising:

one or more instructions for controlling the release of material from a delivery device mounted within a nasal region of a subject, the one or more instructions including;

a control signal generation module capable of generating a delivery control signal corresponding to a desired pattern of delivery of a material into a nasal region of a subject from a delivery portion of the delivery device mounted within the nasal region of the subject; and

at least one of a data storage module capable of storing pattern data or pattern parameters representing the desired pattern of delivery of the material into the nasal region of the subject or a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, wherein the control signal generation module is configured to generate the delivery control signal based upon at least one of the pattern data, pattern parameters, or sense signal.

101. The signal bearing medium of claim 100, the one or more instructions including both a data storage module capable of controlling storage of pattern data or pattern parameters representing the desired pattern of delivery of the material into the nasal region of the subject and a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device.

102. The signal bearing medium of claim 101, wherein the data storage module is capable of storing a sense signal received from the sensing module.

103. The signal bearing medium of claim 102, wherein the data storage module is capable of storing a processed sense signal from the sensor portion of the delivery device.

104. The signal bearing medium of claim 100, the one or more instructions including a user interface module configured to receive user input of one or more user-enterable parameters from a user interface device.

105. The signal bearing medium of claim 100, the one or more instructions including a user interface module configured to receive user input of a desired delivery pattern from a user interface device.

106. The signal bearing medium of claim 105, wherein the user interface module is configured to receive the desired delivery pattern in the form of a digital data transmission.

107. The signal bearing medium of claim 100, the one or more instructions including a data storage module configured to store one or more values from the delivery device.

108. The signal bearing medium of claim 107, wherein the one or more instructions include the sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, and wherein at least a portion of the one or more values are sense signal values received from the sensing module.

109. The signal bearing medium of claim 107, wherein the one or more instructions include the sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, and wherein at least a portion of the one or more values are one or more sense parameters received from the sensing module.

110. The signal bearing medium of claim 107, wherein at least a portion of the one or more values are delivery control signal values from the control signal generation module.

111. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by filtering.

112. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by windowing.

113. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by noise reduction.

114. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by signal averaging.

115. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by feature detection.

116. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by time-domain analysis.

117. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by frequency-domain analysis.

118. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by feature extraction.

119. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by comparing the sense signal with a template sense signal.

120. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by performing sorting.

121. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by performing data reduction.

122. The signal bearing medium of claim 100, the one or more instructions including a sensing module capable of receiving and processing a sense signal from a sensor portion of the delivery device, the sensing module being capable of processing the sense signal by performing endpoint determination.

123. The signal bearing medium of claim 100, wherein the control signal generation module is capable of generating the delivery control signal by calculating the delivery control signal based upon one or more stored parameters.

124. The signal bearing medium of claim 123, wherein at least a portion of the one or more stored parameters are specific to the subject.

125. The signal bearing medium of claim 100, wherein the control signal generation module is capable of generating the delivery control signal from a stored release pattern.

126. The signal bearing medium of claim 101, the one or more instructions including a user interface module configured to receive user input of one or more user-enterable parameters or a desired delivery pattern from a user interface device.