Implantable Bio-Electro-Physiologic Interface Matrix

• US 20080269814A1
• Filed: 05/04/2005
• Published: 10/30/2008
• Est. Priority Date: 05/04/2004
• Status: Active Grant

• Current Assignee: University of Rochester
• Original Assignee: University of Rochester
• Inventors: Rosero, Spencer
• Granted Patent: US 8,849,416 B2
• Time in Patent Office: Days
• US Class Current: 607/6
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/3629 in combination with non-electric therapy
• CPC Class Codes: A61N 1/372 Arrangements in connection with the implantation of stimulators
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula
• CPC Class Codes: A61N 1/37288 Communication to several implantable medical devices within one patient
• CPC Class Codes: A61N 1/37512 Pacemakers
• CPC Class Codes: A61N 1/37514 Brain implants
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

An implantable device (100) having an electronic component (110) and a biologic materials component (130). The biologic materials component has target cells in a matrix that interfaces the electronic component with the surrounding environment.

Claims

1. A device (100) for implantation in a patient, the device comprising:

a biologic component (130) and an electronic component (110) contacting said biologic component.

2. The device of claim 1, wherein said electronic component comprises a wireless communication device.

3. The device of claim 1, wherein said electronic device comprises a communication device that can network said device with other devices.

4. The device of claim 1, wherein said biologic component comprises a cell layer.

5. The device of claim 4, wherein the cell layer includes cells obtained from the patient.

6. The device of claim 1, wherein said biologic component comprises a collagen matrix and cells obtained from the patient grown in the collagen matrix.

7. The device of claim 1, wherein said electronic component comprises a sensor positioned within the biologic component.

8. The device of claim 7, wherein said sensor detects conditions of the biologic component.

9. The device of claim 8, wherein said sensor detects conditions of the patient.

10. The device of claim 1, wherein said electronic component comprises an electrode positioned within the biologic component.

11. The device of claim 10, wherein said electrode stimulates the biologic component.

12. The device of claim 11, wherein said electrode stimulates the patient.

13. A defibrillation device for implantation at a target site in a patient, the device comprising:

a cell layer having cells of interest from the target site of the patient, at least one defibrillation electrode contacting said cell layer for imparting defibrillation energy to the target site of the patient.

14. A method for implanting a device having an electronic component in a patient, the method comprising providing a biologic component, growing the electronic component within the biologic component and implanting the device in the patient.

15. The method of claim 14, wherein the biologic component comprises a cell layer.

16. The method of claim 15, wherein the step of providing a biologic component includes obtaining cells from the patient.

17. The method of claim 14, wherein the step of providing a biologic component comprises providing a collagen matrix, obtaining cells from the patient, and growing the cells in the collagen matrix.

18. The method of claim 14, wherein the electronic component comprises a sensor.

19. The method of claim 18, wherein the sensor detects conditions of the biologic component.

20. The method of claim 18, wherein the sensor detects conditions of the patient.

21. The method of claim 14, wherein the electronic component comprises an electrode.

22. The method of claim 21, wherein said electrode stimulates the biologic component.

23. The method of claim 21, wherein said electrode stimulates the patient.