LOW OXYGEN IN VIVO ANALYTE SENSOR

  • US 20080296155A1
  • Filed: 05/01/2008
  • Published: 12/04/2008
  • Est. Priority Date: 03/04/1997
  • Status: Active Grant
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First Claim
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1. A device for measuring a concentration of glucose in a biological fluid, the device comprising:

  • a glucose determining apparatus comprising an electrode and a membrane impregnated with glucose oxidase, wherein the glucose determining apparatus is configured to determine, in operation, a concentration of glucose in a biological sample via measurement of hydrogen peroxide produced by a reaction of glucose and oxygen with the glucose oxidase; and

    a housing comprising an electronic circuit operatively connected to at least one electrode;

    wherein the glucose determining apparatus is configured to measure glucose concentration with substantial linearity at glucose concentrations of up to about 400 mg/dL at an oxygen concentration of less than about 0.6 mg/L.

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