Multilayer Film With Septum Layer

• US 20080311321A1
• Filed: 06/21/2006
• Published: 12/18/2008
• Est. Priority Date: 06/28/2005
• Status: Abandoned Application

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Sparholt, Philip Albert, Hansen, Lasse
• Application Number:
  US11/917,202
• Publication Number:
  US 20080311321A1
• Time in Patent Office: Days
• US Class Current: 428/35.2
• CPC Class Codes: A61J 1/00 Containers specially adapted for medical or pharmaceutical purposes capsules or the like for oral use A61J3/07; specially adapted for surgical or diagnostic appliances or instruments A61B50/30; containers for radioactive substances G21F5/00
• CPC Class Codes: A61J 1/1406 Septums, pierceable membranes
• CPC Class Codes: B32B 2309/105 Thickness
• CPC Class Codes: B32B 2439/80 Medical packaging
• CPC Class Codes: B32B 25/08 of synthetic resin
• CPC Class Codes: B32B 25/20 comprising silicone rubber
• CPC Class Codes: B32B 27/08 of synthetic resin
• CPC Class Codes: B32B 27/302 comprising aromatic vinyl (co)polymers, e.g. styrenic (co)polymers
• CPC Class Codes: B32B 27/32 comprising polyolefins comprising vinyl (co)polymers or acrylic (co)polymers B32B27/30
• CPC Class Codes: B32B 27/322 comprising halogenated polyolefins, e.g. PTFE
• CPC Class Codes: B32B 27/34 comprising polyamides
• CPC Class Codes: B32B 27/36 comprising polyesters
• CPC Class Codes: B32B 27/40 comprising polyurethanes
• CPC Class Codes: B32B 7/12 using interposed adhesives or interposed materials with bonding properties
• CPC Class Codes: Y10T 428/1334 Nonself-supporting tubular film or bag [e.g., pouch, envelope, packet, etc.]
• CPC Class Codes: Y10T 428/266 of base or substrate
• CPC Class Codes: Y10T 428/2817 Heat sealable
• CPC Class Codes: Y10T 428/2826 Synthetic resin or polymer

Abstract

A flexible multilayer film for forming a container defining a liquid-tight chamber for storing a liquid is described here. The film comprises a first layer (1) and a second layer (2). The first layer (1) is a barrier layer, for example, a PCTFE layer, which is arranged inwardly of the second layer (2) as seen in a direction from the chamber of the container formed from the multilayer film. The second layer (2) is a septum layer, for example, a TPE layer, having self-sealing properties so as to seal around a hypodermic needle penetrating said film. As seen in the above direction an innermost surface (5) of the film is weldable onto itself and is preferably made of a weldable layer (3) comprising PE and/or PP.

Claims

1. A flexible multilayer film for forming a container defining a liquid-tight chamber for storing a liquid, said film comprising a first layer and a second layer, said first layer being a barrier layer and arranged inwardly of said second layer as seen in a direction from the chamber of the container formed from the said film, said second layer being a septum layer having self-sealing properties so as to seal around a hypodermic needle penetrating said film, and as seen in the above direction an innermost surface of said film being weldable.

2. A flexible film according to claim 1, wherein the innermost surface of the film is formed of said first layer.

3. A flexible film according to claim 1, wherein the innermost surface of the film is formed of a third layer being a weldable layer, preferably arranged adjacent the barrier layer.

4. A flexible film according to claim 3, wherein the weldable layer comprises polyethylene (PE) and/or polypropylene (PP).

5. A flexible film according to claim 4, wherein the thickness of the weldable layer is more than approximately 10 μ

m, preferably more than approximately 20 μ

m and less than approximately 60 μ

m, preferably less than approximately 50 μ

m.

6. A flexible film according to claim 2, wherein a fourth layer being also an additional weldable layer is arranged outwardly of the barrier layer and preferably adjacent thereto, said additional weldable layer preferably being identical to the third layer.

7. A flexible film according to claim 1, wherein the barrier layer comprises fluoroplastics, preferably a polychlorotrifluoroethylene layer (PCTFE-layer).

8. A flexible film according to claim 7, wherein the thickness of the barrier is more than approximately 40 μ

m and less than approximately 100 μ

m, preferably less than 75 μ

m.

9. A flexible film according to claim 1, wherein the septum layer has self-sealing properties so that the septum layer reseals itself in the area penetrated by the needle when the needle is removed.

10. A flexible film according to claim 1, wherein the septum layer comprises an elastomer, and preferably comprises a rubber material, for example, silicon rubber, or comprises a thermoplastic elastomer (TPE).

11. A flexible film according to claim 1, wherein the thickness of the septum layer is between about 1000 μ

m and about 100 μ

m, preferably between 700 μ

m and 200 μ

m, and especially between 600 μ

m and 300 μ

m.

12. A flexible film according to claim 1, wherein the hardness of the septum layer is from about 20 to 90 Shore A, preferably from about 30 to 70 Shore A.

14. A flexible film according to claim 1, wherein the film is formed by co-extrusion, extrusion lamination or lamination, and tie layers optionally being arranged between the different layers of the film.

15. A container prepared by a film according to claim 1.

16. A container according to the claim 15, wherein at least 80%, preferably at least 90%, more preferred at least 95%, of the (outer) surface is covered by a septum layer having self-sealing properties.

13. A flexible film according to claim, wherein the multilayer film is at least substantially transparent.

17. (canceled)