EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT

  • US 20090018418A1
  • Filed: 05/09/2008
  • Published: 01/15/2009
  • Est. Priority Date: 05/10/2007
  • Status: Active Grant
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First Claim
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1. An intravascular sensor for determining an analyte concentration in blood comprising:

  • an optical fiber comprising a sensor chemistry portion capable of insertion into a blood vessel, the sensor chemistry portion comprising;

    an analyte binding molecule capable of binding an analyte; and

    a fluorophore associated with the analyte binding molecule, the fluorophore having a first fluorescence when the analyte binding molecule is not bound to the analyte and a second fluorescence when the analyte binding molecule is bound to the analyte;

    a light source; and

    a detector.

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