MASS DEFECT LABELING AND METHODS OF USE THEREOF
First Claim
Patent Images
1. A peptide comprising:
- a mass defect labeled peptide including at least one cysteine, wherein at least one of the cysteine residues are labeled with 2,4-dibromo-acetanilide.
2 Assignments
0 Petitions
Accused Products
Abstract
Briefly described, embodiments of this disclosure include mass defect labeled peptides, methods of identifying peptides, and the like.
2 Citations
8 Claims
-
1. A peptide comprising:
a mass defect labeled peptide including at least one cysteine, wherein at least one of the cysteine residues are labeled with 2,4-dibromo-acetanilide. - View Dependent Claims (2)
-
3. A method of identifying peptides comprising:
-
labeling at least one cysteine in a target peptide with a mass defect label, wherein the mass defect label is 2,4-dibromo-acetanilide; introducing the target peptide to a mass spectrometry system; and obtaining a mass spectrum of the target peptide. - View Dependent Claims (4, 5)
-
-
6. A peptide comprising:
a mass defect labeled peptide including at least one tryptophan, wherein at least one of the tryptophan residues are labeled with 4,6-dibromo-2-trifluoromethylphenylsulfenyl chloride.
-
7. A method of identifying peptides comprising:
-
labeling at least one tryptophan in a target peptide with a mass defect label, wherein the mass defect label is 4,6-dibromo-2-trifluoromethylphenylsulfenyl chloride; introducing the target peptide to a mass spectrometry system; and obtaining a mass spectrum of the target peptide. - View Dependent Claims (8)
-
Specification