METHOD OF TREATING CARDIOMYOPATHY

• US 20090082619A1
• Filed: 12/02/2008
• Published: 03/26/2009
• Est. Priority Date: 06/09/2005
• Status: Abandoned Application

• Current Assignee: University of Miami
• Original Assignee: University of Miami
• Inventors: DE MARCHENA, Eduardo
• Application Number:
  US12/326,432
• Publication Number:
  US 20090082619A1
• Time in Patent Office: Days
• US Class Current: 600/37
• CPC Class Codes: A61B 17/00234 for minimally invasive surgery A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence
• CPC Class Codes: A61B 17/0401 Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors A61B17/0642 takes precedence; fixation devices for tendons or ligaments A61F2/0811
• CPC Class Codes: A61B 17/083 Clips, e.g. resilient
• CPC Class Codes: A61B 17/10 for applying or removing wound clamps, e.g. containing only one clamp or staple A61B17/076 takes precedence; containing multiple wound clamps A61B17/068; Wound clamp magazines containers, packaging elements or packages specially adapted for particular articles or with special means for dispensing contents B65D83/00, B65D85/00
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/0496 for tensioning sutures
• CPC Class Codes: A61F 2/2457 Chordae tendineae prostheses

Abstract

The surgical implantation of a link, which may be in the form of a tether or a looped band, is proposed to connect and reduce the spacing between facing walls of the left ventricle, to reduce dilation of the left ventricle. Decreasing the distance between the facing portions of the ventricle may also more appropriately align the chordal apparatus to decrease mitral regurgitation. The implanted link thus improves heart function by reducing left ventricular failure.

Claims

1. A method of reducing a transventricular size and improving ventricular geometry in a patient having dilated cardiomyopathy, comprising:

securing a first end of a tether structure to one of the papillary muscles of the left ventricle of the patient'"'"'s heart;

securing a second end of the tether structure to an opposing interior surface of the left ventricle of the patient'"'"'s heart; and

reducing a distance between said papillary muscle and said opposing interior surface by drawing the papillary muscle and the opposing interior surface together with said at least one tether structure to reduce a transventricular size and geometry of the patient'"'"'s heart, thereby to mitigate the affects of the dilated cardiomyopathy.

2. A method as in claim 1, wherein the opposing interior surface of the left ventricle is the inter-ventricular septum.

3. A method as in claim 2, wherein said tether structure comprises first and second suture filaments, wherein a clip is attached to an end of each suture filament, and wherein said securing steps comprise securing the clip of the first suture filament to the papillary muscle and securing the clip of the second suture filament to the inter-ventricular septum.

4. A method as in claim 3, further comprising advancing a clip applying device carrying the first and second suture filaments through said guide catheter.

5. A method as in claim 3, wherein the reducing step comprises:

drawing the clips of the first and second suture filaments together to thereby reduce a distance between said papillary muscle and said inter-ventricular septum; and

attaching ends of the suture filaments together.

6. A method as in claim 1, wherein the opposing interior surface of the left ventricle is an exterior wall of the left ventricle.

7. A method as in claim 1, wherein said tether structure comprises first and second suture filaments, wherein a clip is attached to an end of each suture filament, and wherein said securing steps comprise securing the clip of the first suture filament to the papillary muscle and securing the clip of the second suture filament to the exterior wall of the left ventricle.

8. A method as in claim 7, further comprising advancing a clip applying device carrying the first and second suture filaments through said guide catheter.

9. A method as in claim 7, wherein the reducing step comprises:

drawing the clips of the first and second suture filaments together to thereby reduce a distance between said papillary muscle and said exterior wall of the left ventricle; and

attaching ends of the suture filaments together.

10. A method as in claim 1, further comprising, before performing said securing steps, accessing the patient'"'"'s vasculature remote from the heart, and advancing a guide catheter through the patient'"'"'s vasculature so that a distal end thereof is disposed in the left ventricle of the patient'"'"'s heart.

11. A method as in claim 10, further comprising, before advancing said guide catheter, creating a trans-septal opening with a needle knife disposed through a catheter.

12. A method as in claim 1, further comprising visualizing the papillary muscle and adjacent ventricular structures via fluoroscopy, or intra-cardiac ultrasound during said securing and reducing steps.

13. A method of reducing a transventricular size and improving ventricular geometry in a patient having dilated cardiomyopathy, comprising:

securing a first end of a tether structure to an exterior wall of the left ventricle of the patient'"'"'s heart;

securing a second end of the tether structure to the inter-ventricular septum; and

reducing a distance between said exterior wall of the left ventricle and said inter-ventricular septum by drawing the exterior wall and the inter-ventricular septum together with said at least one tether structure to reduce a transventricular size and geometry of the patient'"'"'s heart, thereby to mitigate the affects of the dilated cardiomyopathy.

14. A method as in claim 13, further comprising, before performing said securing steps, accessing the patient'"'"'s vasculature remote from the heart, and advancing a guide catheter through the patient'"'"'s vasculature so that a distal end thereof is disposed in the left ventricle of the patient'"'"'s heart.

15. A method as in claim 14, further comprising, before advancing said guide catheter, creating a trans-septal opening with a needle knife disposed through a catheter.

16. A method as in claim 13, wherein said tether structure comprises first and second suture filaments, wherein a clip is attached to an end of each suture filament, and wherein said securing steps comprise securing the clip of the first suture filament to the exterior wall of the left ventricle and securing the clip of the second suture filament to the inter-ventricular septum.

17. A method as in claim 16, further comprising advancing a clip applying device carrying the first and second suture filaments through said guide catheter.

18. A method as in claim 16, wherein the reducing step comprises:

drawing the clips of the first and second suture filaments together to thereby reduce a distance between said exterior wall of the left ventricle and said inter-ventricular septum; and

attaching ends of the suture filaments together.

19. A method as in claim 13, further comprising visualizing the ventricular structures via fluoroscopy, or intra-cardiac ultrasound during said securing and reducing steps.