SYSTEMS AND METHODS FOR REPLACING SIGNAL ARTIFACTS IN A GLUCOSE SENSOR DATA STREAM

• US 20090124878A1
• Filed: 01/14/2009
• Published: 05/14/2009
• Est. Priority Date: 08/22/2003
• Status: Active Grant

Abstract

Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.

Claims

1. A system for processing data signals obtained from a glucose sensor, the system comprising:

a receiving module that receives a signal from a glucose sensor over a period of time; and

a processor module comprising programming that detects transient non-glucose related signal artifacts and replaces at least some of the signal artifacts with estimated glucose values.

2. The system of claim 1, further comprising a glucose sensor.

3. The system of claim 1, wherein the programming configured to replace at least some of the signal artifacts is configured to output the estimated glucose values in response to detection of transient non-glucose related signal artifacts, wherein the estimated glucose values comprise filtered, calibrated glucose values.

4. The system of claim 3, wherein the processor module further comprises programming configured to output unfiltered, calibrated glucose values when transient non-glucose related signal artifacts are not detected.

5. A system for processing data signals obtained from a glucose sensor, the system comprising:

a receiving module that receives a signal from a glucose sensor over a period of time; and

a processor module comprising programming that detects transient non-glucose related signal artifacts and outputs estimated glucose values during transient non-glucose related signal artifacts.

6. The system of claim 5, further comprising a glucose sensor.

7. The system of claim 5, wherein the programming configured to output estimated glucose values during transient non-glucose related signal artifacts is configured to display data representative of the estimated glucose values, including at least one of a numeric representation of the estimated glucose values, an indication of directional trend of the estimated glucose values, and a graphical representation of the estimated glucose values in response to detection of transient non-glucose related signal artifacts, wherein the estimated glucose values comprise filtered, calibrated glucose values.

8. The system of claim 7, wherein the processor module further comprises programming configured to output unfiltered, calibrated glucose values when transient non-glucose related signal artifacts are not detected.

9. A system for processing data signals obtained from a glucose sensor, the system comprising:

a receiving module that receives a signal from a glucose sensor over a period of time; and

a processor module comprising programming that detects transient non-glucose related signal artifacts and selectively displays unfiltered glucose values when signal artifacts are not detected and filtered glucose values when signal artifacts are detected.

10. The system of claim 9, further comprising a glucose sensor.

11. The system of claim 9, wherein the unfiltered glucose values are calibrated unfiltered glucose values.

12. The system of claim 9, wherein the filtered glucose values are calibrated filtered glucose values.

13. The system of claim 9, wherein the programming that displays is configured to display at least one of a numeric representation of the glucose values, an indication of directional trend of the glucose values, and a graphical representation of the glucose values.