polymorphous forms of rifaximin, processes for their production and use thereof in the medicinal preparations

  • US 20090130201A1
  • Filed: 02/27/2006
  • Published: 05/21/2009
  • Est. Priority Date: 03/03/2005
  • Status: Active Grant
First Claim
Patent Images

1. Polymorph of the antibiotic rifaximin called rifaximin S characterized from a water content in the range from 2.5% (w/w) to 6% (w/w), preferably comprised between 3.0% and 4.5%, and from a powder X-ray diffractogram showing peaks at values of the diffraction angles 2θ

  • of 5.7°

    ±

    0.2, 6.7°

    10.2, 7.1°

    10.2, 8.0°

    ±

    0.2, 8.7°

    ±

    0.2, 10.4°

    ±

    0.2, 10.8°

    ±

    0.2, 11.3°

    10.2, 12.1°

    ±

    0.2, 17.0°

    10.2, 17.3°

    ±

    0.2, 17.5°

    ±

    0.2, 18.5°

    ±

    0.2, 18.8°

    010.2, 19.1°

    ±

    0.2, 21.0°

    00.2, 21.5°

    ±

    0.2.

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