ENZYME SUBSTRATE COMPRISING A FUNCTIONAL DYE AND ASSOCIATED TECHNOLOGY AND METHODS

  • US 20090148386A1
  • Filed: 11/21/2006
  • Published: 06/11/2009
  • Est. Priority Date: 11/30/2005
  • Status: Active Grant
First Claim
Patent Images

1. A substrate selected from a compound having a structural formula, DYE-(B)m, and a pro-enzyme substrate thereof, wherein DYE, when independent of DYE-(B)m, comprises a dye selected from a biologically functional fluorescent dye and a fluorogenic dye, the dye being capable of binding to a partner biomolecule, partner biomolecules, or an assembly of partner biomolecules;

  • wherein m is selected from 1, 2, 3, 4 and 5; and

    wherein each of at least one B, independently, comprises an enzyme substrate moiety that is capable of enzymatic transformation comprising cleavage of a bond involving the dye and at least one B, cleavage of a bond within at least one B, or formation of a bond involving at least one B.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×