Non-Invasive Fetal Genetic Screening by Digital Analysis

  • US 20090170113A1
  • Filed: 02/26/2009
  • Published: 07/02/2009
  • Est. Priority Date: 02/02/2006
  • Status: Active Grant
First Claim
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1. A method of differential detection of target sequences in a mixture of maternal and fetal genetic material, comprising the steps of:

  • a) obtaining maternal tissue containing both maternal and fetal genetic material;

    b) distributing the genetic material into discrete samples, each sample containing on average not more than about one target sequence per sample;

    c) measuring the presence of different target sequences in the discrete samples; and

    d) analyzing a number of the discrete samples sufficient to obtain results distinguishing different target sequences.

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