TRANSCUTANEOUS ANALYTE SENSOR

  • US 20090192724A1
  • Filed: 02/03/2009
  • Published: 07/30/2009
  • Est. Priority Date: 08/01/2003
  • Status: Active Grant
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First Claim
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1. A device for monitoring glucose concentration in a biological sample of a host, the device comprising:

  • a substantially continuous glucose sensor that produces a data stream indicative of a glucose concentration in a host, the data stream comprising a plurality of time spaced sensor data points;

    an integrated receiver that receives the data stream from the substantially continuous glucose sensor, wherein the integrated receiver comprises;

    an in vitro single point glucose monitor configured to receive a biological sample from the host and to measure the concentration of glucose in the sample;

    a processor; and

    a computer readable memory comprising;

    instructions configured to cause the processor to calibrate the data stream received from the continuous glucose sensor;

    instructions configured to cause the processor to determine a rate of change of the calibrated data stream from the substantially continuous analyte sensor; and

    instructions configured to cause the processor to not re-calibrate and/or update calibration of the data stream using a glucose concentration measured by the single point glucose monitor when the rate of change of the calibrated data stream is determined to be aberrant, wherein the rate of change of the calibrated data stream is determined to be aberrant when the rate of change of the calibrated data stream is greater than +/−

    2 mg/dL/min.

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