METHOD FOR TRANSMITTING DATA IN A BLOOD GLUCOSE SYSTEM AND CORRESPONDING BLOOD GLUCOSE SYSTEM

• US 20090216100A1
• Filed: 04/20/2006
• Published: 08/27/2009
• Est. Priority Date: 04/20/2006
• Status: Active Grant

• Current Assignee: Cilag Gmbh International (Johnson & Johnson)
• Original Assignee: LifeScan Scotland Limited (Johnson & Johnson)
• Inventors: Ebner, Manfred, Kraft, Ulrich
• Granted Patent: US 8,099,074 B2
• Time in Patent Office: Days
• US Class Current: 600/347
• CPC Class Codes: A61B 2560/0209 adapted for power saving
• CPC Class Codes: A61B 5/0002 Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network A61B5/07 takes precedence; transmission systems for measured values G08C; transmission H04B; transmission of digital information H04L; wireless communication networks H04W
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 2205/3569 sublocal, e.g. between console and disposable
• CPC Class Codes: A61M 2230/201 Glucose concentration
• CPC Class Codes: A61M 5/14244 adapted to be carried by the patient, e.g. portable on the body
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00
• CPC Class Codes: H04B 7/24 for communication between two or more posts wireless communication networks H04W
• CPC Class Codes: H04W 52/0216 using a pre-established activity schedule, e.g. traffic indication frame
• CPC Class Codes: H04W 52/0225 using monitoring of external events, e.g. the presence of a signal
• CPC Class Codes: Y02D 30/70 in wireless communication networks

Abstract

The present invention relates to a method for wireless transmission of data between components of a blood glucose system (1, I1) including a master controller (2, 2′) having a receiver (10) and a transmitter (9), and at least one slave device (3) having a receiver (19) and a transmitter (18), and to a corresponding blood glucose system (1, I1). The slave device (3) is normally operated in a power saving mode in which its receiver (19) is only activated intermittently at a receiver activation frequency for a predetermined listening period. The controller (2, 21) transmits a communication initiation data frame to the slave device (3) by means of a signal comprising a preamble signal transmitted for a preamble period. Upon receipt of the communication initiation data frame, the slave device (3) is switched to a communication mode in which it transmits a response to the controller (2, 21), and the slave device (3) is switched from the communication mode to the power saving mode. Initially the receiver activation frequency is set to a first frequency value upon switching from communication mode to power saving mode, and then to a second frequency value smaller than the first frequency value if no communication initiation data frame is received for a predetermined power saving timeout period. The communication initiation data frame is transmitted such that the preamble period exceeds the length of the cycle duration corresponding to the first frequency value, and, in case no response is received by the controller during the response period, the communication initiation data frame is adapted and retransmitted such that the preamble period is increased and exceeds the length of the cycle duration corresponding to the second frequency value.

Claims

1. A method for wireless transmission of data between components of a blood glucose system including a master controller having a receiver and a transmitter, and a slave device comprising an insulin dispensing means and having a receiver and a transmitter, the method comprises the following steps:

operating the slave device normally in a power saving mode in which its receiver is activated intermittently at a receiver activation frequency, with the receiver each time being activated for a predetermined listening period and the receiver being deactivated for the rest of the time,

activating the transmitter of the controller for a transmission period to transmit a communication initiation data frame including a preamble portion which is chosen such that a preamble signal is transmitted for a preamble period, and subsequently activating the receiver of the controller for a response period, and

in case the slave device receives the preamble signal during a listening period,

a) maintaining the receiver of the slave device active until at least a portion of the remainder of the communication initiation data frame has been received,

b) switching the slave device to a communication mode in which the transmitter of the slave device is activated to transmit a response to the controller, and

c) switching the slave device from the communication mode to the power saving mode,

initially setting the receiver activation frequency to a first frequency value upon switching from communication mode to power saving mode, and setting the receiver activation frequency to a second frequency value smaller than the first frequency value if no communication initiation data frame is received for a predetermined power saving timeout period, wherein

the communication initiation data frame is transmitted such that the preamble period exceeds the length of the cycle duration corresponding to the first frequency value, and, in case no response is received by the controller during the response period, the communication initiation data frame is adapted and retransmitted such that the preamble period is increased and exceeds the length of the cycle duration corresponding to the second frequency value.

2. The method according to claim 1, wherein the blood glucose system includes at least one further slave device, at least one of which comprises a blood glucose sensing means, wherein all slave devices perform the same steps as the slave device comprising an insulin dispensing means, and wherein the method further comprises the following steps:

including an indication of a target slave device in communication initiation data frames transmitted by the controller in order to address each communication initiation data frame to a particular slave device, and

in case a slave device receives the preamble signal corresponding to a communication initiation data frame during a listening period;

a) maintaining the receiver of the slave device active at least until the target device indication has been received, and

b) maintaining the receiver of the slave device active until the remainder of the communication initiation data frame has been received if the slave device is the target slave device, or, in case the slave device is not the target slave device, maintaining the slave device in the power saving mode and setting the activation frequency for the slave device to a third frequency value greater than the second frequency value and subsequently setting the activation frequency to the second frequency value if no communication initiation data frame is received for a predetermined timeout period.

3. The method according to claim 2, wherein the third frequency value is identical to the first frequency value.

4. The method according to claim 1, wherein the controller only transmits communication initiation data frames.

5. The method according to claim 1, further comprising the following steps:

following transmission of a communication initiation data frame, activating the transmitter of the controller for at least one further transmission period to transmit at least one further data frame including a preamble portion which is chosen such that the preamble signal is transmitted for a preamble period, and, following transmission of each of the at least one further data frame, activating the receiver of the controller for a response period, wherein all data frames transmitted by the controller include a command portion in which a command is included,

including a communication initiation command in the command portion of any communication initiation data frame to indicate that this data frame is a communication initiation data frame,

in case a slave device receives the preamble signal during a listening period while it is in the power saving mode;

a) maintaining the receiver of the slave device active at least until the command included in the command portion of the data frame has been received, and

b) maintaining the slave device in the power saving mode in case the command is not the communication initiation command, and

in case a slave device receives the preamble signal while it is in the communication mode;

a) maintaining the receiver of the slave device active at least until the command included in the command portion of the data frame has been received, and

b) if the command is not the communication initiation command and the slave device is the intended recipient of the data frame, maintaining the receiver of the slave device active until the remainder of the data frame has been received, and activating and deactivating the transmitter of the slave device to transmit a response to the controller.

6. The method according to claim 1, wherein the communication mode is terminated if no data frame for the respective slave device is received for a predetermined communication timeout period, and wherein in communication mode the receiver of the respective slave device is maintained active whenever its transmitter is not activated to transmit a response.

7. The method according to claim 6, further comprising the steps of tracking at the controller the time since transmitting the last data frame to a particular slave device, determining at the controller, prior to transmitting a data frame to the same slave device, based on a comparison between the tracked time and the predetermined communication timeout period whether this slave device is expected to still be in communication mode, and, if it is determined that the slave device is expected to still be in communication mode, initially transmitting the data frame such that the preamble period spans a time period shorter than the cycle durations corresponding to the first frequency value and the second frequency value.

8. The method according to claim 7, further comprising the steps of:

including a delay time period indication into a response transmitted by a slave device to a particular first data frame to indicate that the actual response will be transmitted later,

deactivating the transmitter and the receiver of both the slave device and the controller for the indicated delay time period,

activating the transmitter of the controller after the end of the delay time period to transmit a second data frame requesting the response to the first data frame,

activating the receiver of the slave device after the end of the delay time period to wait for the receipt of the second data frame, and

subsequently activating the transmitter of the slave device to transmit the requested response to the controller.

9. The method according to claim 1, wherein a data frame including a termination command is transmitted by means of the controller to a slave device in communication mode, and wherein the communication mode of the slave device is terminated upon receipt of this data frame.

10. The method according to claim 1, wherein the transmission of at least one communication initiation data frame by the controller is initiated by user request.

11. The method according to claim 1, further comprising the steps of periodically generating a timer event in the controller, and transmitting a communication initiation data frame by the controller upon each occurrence of a timer event.

12. The method according to claim 11, further comprising the steps of:

choosing the frequency at which the timer events occur to have the second frequency value or such that the second frequency value is an integral multiple of the timer event frequency,

including a time reference in each communication initiation data frame initiated by a timer event,

examining the time reference upon receipt at a slave device, and

synchronizing by means of the time reference the start times of the listening periods with the timer events.

13. A blood glucose system comprising

a master controller having a receiver, a transmitter and a control means, wherein the control means is operable to activate the transmitter for a transmission period in order to transmit a communication initiation data frame including a preamble portion such that a preamble signal is transmitted for a preamble period, and to subsequently activate the receiver for a response period,

a slave device comprising an insulin dispensing means and having a receiver, a transmitter and a control means, wherein the slave device is adapted to be worn on or to be implanted subcutaneously into the body of a patient such that insulin can be delivered from the slave device to the body of the patient,

wherein the control means of the slave device is adapted to operate the slave device normally in a power saving mode in which the control means activates the receiver intermittently at a receiver activation frequency, with the receiver each time being activated for a predetermined listening period and the receiver being deactivated for the rest of the time, and

wherein the control means of the slave device is further adapted to determine whether the receiver of the slave device receives the preamble signal during a listening period, and in case the preamble signal is received to

a) maintain the receiver of the slave device active until at least a portion of the remainder of the communication initiation data frame has been received,

b) switch the slave device to a communication mode in which the control means activates the transmitter of the slave device to transmit a response to the controller, and

c) subsequently switch the slave device from the communication mode to the power saving mode,

wherein

the control means of the slave device is adapted to initially set the activation frequency to a first frequency value upon switching the slave device from communication mode to power saving mode, and to set the activation frequency to a second frequency value smaller than the first frequency value if the receiver does not receive a communication initiation data frame for a predetermined power saving timeout period, wherein

the control means of the controller is adapted to effect transmission the communication initiation data frame such that the preamble period exceeds the length of the cycle duration corresponding to the first frequency value, and, in case no response is received during the response period, to adapt and retransmit the communication initiation data frame such that the preamble period is increased and exceeds the length of the cycle duration corresponding to the second frequency value.

14. The system according to claim 13, wherein the blood glucose system includes at least one further slave device, at least one of which comprises a blood glucose sensing means, wherein all slave devices comprise a receiver, a transmitter and a control means configured in the same way as the receiver, the transmitter and the control means respectively, of the slave device comprising an insulin dispensing means, and wherein:

the control means of the controller is further adapted to include an indication of a target slave device in the communication initiation data frame, and

wherein the control means of the slave devices is further adapted to

a) maintain the receiver of the slave device active at least until the receiver has received the target device indication, and

b) maintain the receiver of the slave device active until the remainder of the communication initiation data frame has been received if the slave device is the target slave device, or, in case the slave device is not the target slave device, maintain the slave device in the power saving mode, and set the receiver activation frequency for the slave device to a third frequency value greater than the second frequency value and subsequently set the receiver activation frequency to the second frequency value if the receiver does not receive a communication initiation data frame for a predetermined timeout period,

in case the control means determines that the slave device receives the preamble signal during a listening period.

15. The system according to claim 13, wherein

following transmission of a communication initiation data frame, the control means of the controller is further operable to activate the transmitter of the controller for at least one further transmission period to transmit at least one further data frame including a preamble portion such that the preamble signal is transmitted for a preamble period, and, following transmission of each of the at least one further data frame, to activate the receiver of the controller for a response period, wherein all data frames transmitted by the controller include a command portion in which a command is included,

the control means of the controller is further adapted to include a communication initiation command in the command portion of any communication initiation data frame to indicate that this data frame is a communication initiation data frame,

the control means of the slave devices is further adapted to determine whether the receiver of the slave device receives the preamble signal during a listening period while it is in the power saving mode, and in case this determination is positive to

a) maintain the receiver of the slave device active at least until the command included in the command portion of the data frame has been received, and

b) maintain the slave device in the power saving mode in case the command is not the communication initiation command, and

the control means of the slave devices is further adapted to determine whether the receiver of the slave device receives the preamble signal while it is in the communication mode, and in case this determination is positive to:

a) maintain the receiver of the slave device active at least until the command included in the command portion of the data frame has been received, and

b) if the command is not the communication initiation command and the slave device is the intended recipient of the data frame, maintain the receiver of the slave device active until the remainder of the data frame has been received, and activate and deactivate the transmitter of the slave device to transmit a response to the controller.

16. The system according to claim 13, wherein the control means of each slave device is adapted to terminate the communication mode if the receiver does not receive a data frame for the respective slave device for a predetermined communication timeout period, and to maintain the receiver of the respective slave device active in communication mode whenever it does not activate the transmitter to transmit a response.

17. The system according to 16, wherein the controller further includes a timer, and wherein the control means of the controller is adapted to start the timer upon transmitting a data frame to a particular slave device, to determine, prior to transmitting a data frame to the same slave device, based on a comparison between the current value of the timer and the predetermined communication timeout period whether the slave device is expected to still be in communication mode, and in case it determines that the slave device is expected to still be in communication mode to initially transmit the data frame such that the preamble period spans a time period shorter than the cycle durations corresponding to the first frequency value and the second frequency value.

18. The system according to claim 16, wherein

the control means of each slave device is adapted to include a delay time period indication into a response transmitted by the slave device, to a particular first data frame to indicate that the actual response will be transmitted later, to deactivate the transmitter and the receiver for the indicated delay time period, to activate the receiver of the slave device after the end of the delay time period to wait for the receipt of a second data frame requesting the response to the first data frame, and to subsequently activate the transmitter of the slave device to transmit the requested response to the controller and wherein

the control means of the controller is adapted to deactivate, upon receipt of a response including a delay time period indication, the transmitter and the receiver of the controller for the indicated delay time period, and to activate the transmitter of the controller after the end of the delay time period to transmit a second data frame requesting the response to the first data frame.

19. The system according to claim 13, wherein the control means of the controller is operable to transmit a data frame including a termination command to a slave device in communication mode, and wherein the control means of each slave device is adapted to terminate the communication mode upon receipt of this data frame.

20. The system according to claim 13, wherein the controller comprises an actuation means to be actuated by a user, wherein actuation of the actuation means provides a signal to the control means instructing the control means to transmit a communication initiation data frame.

21. The system according to claim 13, wherein the controller further comprises a timer event generator operable to periodically generate a timer event and to provide corresponding timer event signals to the control means of the controller, and wherein the control means of the controller is adapted to transmit a communication initiation data frame upon receipt of such a timer event signal.

22. The system according to claim 21, wherein

the frequency with which the timer event generator generates the timer events has the second frequency value or is such that the second frequency value is an integral multiple of the timer event frequency,

the controller comprises a clock and the control means of the controller is adapted to include a time reference derived from the clock in each data frame initiated by the receipt of a timer event signal, and

the control means of the slave devices are adapted to examine the time reference upon receipt at a slave device, and to synchronize by means of the time reference the start times of the listening periods with the timer events.

23. The system according to claim 13, wherein the controller includes a blood glucose sensing means.