Methods and systems for presenting a combination treatment

• US 20090270786A1
• Filed: 11/26/2008
• Published: 10/29/2009
• Est. Priority Date: 04/24/2008
• Status: Active Grant

• Current Assignee: Harvest Bio LLC
• Original Assignee: Searete LLC (Intellectual Ventures LLC)
• Inventors: Ishikawa, Muriel Y., Lord, Robert W., Levien, Royce A., Wood, Lowell L. JR., Hyde, Roderick A., Malamud, Mark A., Sweeney, Elizabeth A., Wood, Victoria Y.H., Leuthardt, Eric C.
• Granted Patent: US 8,682,687 B2
• Time in Patent Office: Days
• US Class Current: 604/19
• CPC Class Codes: A61B 5/00 Measuring for diagnostic purposes radiation diagnosis A61B6/00; diagnosis by ultrasonic, sonic or infrasonic waves A61B8/00; Identification of persons
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/415 the glands, e.g. tonsils, adenoids or thymus
• CPC Class Codes: A61B 5/416 the spleen
• CPC Class Codes: A61B 5/418 lymph vessels, ducts or nodes
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61M 31/002 Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time artificial gland structures or devices A61F2/022; intra-uterine contraceptive devices A61F6/14; tampons for introducing into the vagina A61F13/20, A61L15/00; suppositories or bougies for intra-vaginal or intra-uterine application A61K9/02; physical forms of medicinal preparations for sustained or differential drug release A61K9/20, A61K9/50
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 40/20 for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms

Abstract

Methods, computer program products, and systems are described that include accepting an indication of a schedule for administration of a bioactive agent to an individual and presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual.

Claims

1. A computer-implemented method, comprising:

accepting an indication of a schedule for administration of a bioactive agent to an individual; and

presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual.

2-43. -43. (canceled)

44. A system, comprising:

means for accepting an indication of a schedule for administration of a bioactive agent to an individual; and

means for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual.

45. The system of claim 44, wherein the means for accepting an indication of a schedule for administration of a bioactive agent to an individual comprises:

means for accepting a bioactive agent time schedule.

46. The system of claim 44, wherein the means for accepting an indication of a schedule for administration of a bioactive agent to an individual comprises:

means for accepting at least one of a bioactive agent delivery type or bioactive agent delivery dosage administration schedule.

47. The system of claim 44, wherein the means for accepting an indication of a schedule for administration of a bioactive agent to an individual comprises:

means for accepting a bioactive agent loading dose.

48. The system of claim 44, further comprising:

means for accepting an indication of at least one of a pharmacokinetic or pharmacodynamic profile of a bioactive agent.

49. The system of claim 48, wherein the means for accepting an indication of at least one of a pharmacokinetic or pharmacodynamic profile of a bioactive agent comprises:

means for accepting an indication of a time versus concentration representation for a bioactive agent.

50. The system of claim 48, wherein the means for accepting an indication of at least one of a pharmacokinetic or pharmacodynamic profile of a bioactive agent comprises:

means for accepting an indication of a dose versus response representation for a bioactive agent.

53. The system of claim 48, wherein the means for accepting an indication of at least one of a pharmacokinetic or pharmacodynamic profile of a bioactive agent comprises:

means for accepting a pharmacokinetic model.

54. The system of claim 53, wherein the means for accepting a pharmacokinetic model comprises:

means for accepting a physiologically-based pharmacokinetic model.

56. The system of claim 53, wherein the means for accepting a pharmacokinetic model comprises:

means for accepting an output from physiologically-based pharmacokinetic modeling software.

57. The system of claim 48, wherein the means for accepting an indication of at least one of a pharmacokinetic or pharmacodynamic profile of a bioactive agent comprises:

means for accepting pharmacokinetic profile information for a bioactive agent including at least one of an absorption characterisitic, a distribution characteristic, a metabolization characteristic, or an excretion characteristic.

58. The system of claim 48, wherein the means for accepting an indication of at least one of a pharmacokinetic or pharmacodynamic profile of a bioactive agent comprises:

means for accepting an indication of a pharmacokinetic profile at least partly based on at least one attribute of the individual.

62. The system of claim 48, wherein the means for accepting an indication of at least one of a pharmacokinetic or pharmacodynamic profile of a bioactive agent comprises:

means for accepting at least one of a Tmin, Tmax, Cmin, or a Cmax value for the bioactive agent.

63. The system of claim 44, wherein the means for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual comprises:

means for presenting an indication of a prescribed artificial sensory experience.

70. The system of claim 44, wherein the means for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual comprises:

means for utilizing an algorithm for recommending at least one artificial sensory experience.

71. The system of claim 70, wherein the means for utilizing an algorithm for recommending at least one artificial sensory experience comprises:

means for utilizing pharmacokinetic modeling software.

72. The system of claim 70, wherein the means for utilizing an algorithm for recommending at least one artificial sensory experience comprises:

means for utilizing pharmacodynamic modeling software.

73. The system of claim 70, wherein the means for utilizing an algorithm for recommending at least one artificial sensory experience comprises:

means for utilizing an algorithm configured for identifying a contraindication of the artificial sensory experience.

74. The system of claim 44, wherein the means for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual comprises:

means for presenting an indication of an artificial sensory experience at least partly based on a personal medical history.

75. The system of claim 44, wherein the means for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual comprises:

means for presenting an indication of an artificial sensory experience at least partly based on experimental data.

76. The system of claim 44, wherein the means for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual comprises:

means for presenting an indication of an artificial sensory experience at least partly based on a medical reference tool.

77. The system of claim 44, wherein the means for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual comprises:

means for presenting the indication to at least one output device.

80. The system of claim 44, wherein the means for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual comprises:

means for presenting the indication to a third party.

81. The system of claim 80, wherein the means for presenting the indication to a third party comprises:

means for presenting the indication to a health care provider.

82. The system of claim 80, wherein the means for presenting the indication to a third party comprises:

means for selectively presenting the indication only to the individual.

83. The system of claim 44, wherein the means for accepting an indication of a schedule for administration of a bioactive agent to an individual and means for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual comprises:

means for accepting the pharmacokinetic profile of immediate release oxycodone, means for accepting a prescribed administration schedule of the immediate release oxycodone to an individual, and means for presenting a prescription for engagement of the individual with a virtual world experience at times when the plasma concentration of the immediate release oxycodone is expected to be below a substantially effective level based on the pharmacokinetic profile of the immediate release oxycodone and the prescribed administration schedule of the immediate release oxycodone.

51-52. -52. (canceled)

55. (canceled)

59-61. -61. (canceled)

64-69. -69. (canceled)

78-79. -79. (canceled)

84-86. -86. (canceled)

87. A system, comprising:

circuitry for accepting an indication of a schedule for administration of a bioactive agent to an individual; and

circuitry for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual.

88. A computer program product comprising:

a signal-bearing medium bearing

one or more instructions for accepting an indication of a schedule for administration of a bioactive agent to an individual; and

one or more instructions for presenting an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual.

89. The computer program product of claim 88, wherein the signal-bearing medium includes a computer-readable medium.

90. The computer program product of claim 88, wherein the signal-bearing medium includes a recordable medium.

91. The computer program product of claim 88, wherein the signal-bearing medium includes a communications medium.

92. A system comprising:

a computing device; and

instructions that when executed on the computing device cause the computing device to accept an indication of a schedule for administration of a bioactive agent to an individual; and

present an indication of an artificial sensory experience at least partly based on the accepting an indication of the schedule for administration of the bioactive agent to the individual.

93. The system of claim 92 wherein the computing device comprises:

one or more of a personal digital assistant (PDA), a personal entertainment device, a mobile phone, a laptop computer, a tablet personal computer, a networked computer, a computing system comprised of a cluster of processors, a computing system comprised of a cluster of servers, a workstation computer, and/or a desktop computer.

94. The system of claim 92, wherein the computing device is operable to accept the at least one attribute of the at least one individual and present the indication of the at least one prescription medication and the at least one artificial sensory experience from at least one memory.