Microelectrode Array System With Integrated Reference Microelectrodes To Reduce Detected Electrical Noise And Improve Selectivity Of Activation
First Claim
1. A microelectrode array system used to sense physiological signals and stimulate signals in a conductive complex physiological solution, comprising:
- a dielectric substrate;
a two dimensional array of signal microelectrodes substantially perpendicular to and integrated on the dielectric substrate, wherein each signal microelectrode in the array has a predetermined height relative to the dielectric substrate; and
at least one reference microelectrode located adjacent to and integrated with the signal microelectrodes on the dielectric substrate, wherein the reference microelectrodes are positioned on the dielectric substrate relative to the signal microelectrodes to enable a reduced level of electrical noise to be detected between the reference microelectrodes and the signal microelectrodes.
2 Assignments
0 Petitions
Accused Products
Abstract
A microelectrode array system used to sense physiological signals and stimulate physiological tissue to form signals is disclosed. The array includes a dielectric substrate and a two dimensional array of signal microelectrodes substantially perpendicular to and integrated on the dielectric substrate. At least one reference microelectrode is located adjacent to and integrated with the signal microelectrodes on the dielectric substrate. The reference microelectrodes are positioned on the dielectric substrate relative to the signal microelectrodes to enable a reduced level of electrical noise to be detected between the reference microelectrodes and the recording microelectrodes.
39 Citations
20 Claims
-
1. A microelectrode array system used to sense physiological signals and stimulate signals in a conductive complex physiological solution, comprising:
-
a dielectric substrate; a two dimensional array of signal microelectrodes substantially perpendicular to and integrated on the dielectric substrate, wherein each signal microelectrode in the array has a predetermined height relative to the dielectric substrate; and at least one reference microelectrode located adjacent to and integrated with the signal microelectrodes on the dielectric substrate, wherein the reference microelectrodes are positioned on the dielectric substrate relative to the signal microelectrodes to enable a reduced level of electrical noise to be detected between the reference microelectrodes and the signal microelectrodes. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
-
-
17. A method of sensing physiological signals and stimulating signals in a complex physiological solution, comprising:
-
implanting an array of signal microelectrodes integrated on a dielectric substrate into a patient such that the signal microelectrodes are proximate to at least one of neural tissue and nerve tissue, said array having a plurality of reference microelectrodes integrated onto the dielectric substrate sufficient to enable a reduced level of electrical noise to be detected between the reference microelectrodes and the signal microelectrodes; and performing at least one of sensing the physiological signals between at least one of the signal microelectrodes and at least one of the reference microelectrodes and stimulating the signals in the conductive complex physiological solution by injecting a current between the at least one signal microelectrode and the at least one reference microelectrode. - View Dependent Claims (18, 19, 20)
-
Specification