Method and Apparatus for Providing Glycemic Control

• US 20090299152A1
• Filed: 06/01/2009
• Published: 12/03/2009
• Est. Priority Date: 05/30/2008
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Dunn, Timothy Christian, Taub, Marc Barry, Crouther, Nathan Christopher
• Granted Patent: US 8,924,159 B2
• Time in Patent Office: Days
• US Class Current: 600/300
• CPC Class Codes: A61B 5/0004 characterised by the type of physiological signal transmitted
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14546 for measuring analytes not otherwise provided for, e.g. ions, cytochromes
• CPC Class Codes: A61B 5/14865 invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
• CPC Class Codes: A61B 5/1495 Calibrating or testing of in-vivo probes
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61B 5/4848 Monitoring or testing the effects of treatment, e.g. of medication
• CPC Class Codes: A61B 5/486 Bio-feedback A61B5/375 takes precedence
• CPC Class Codes: A61B 5/4866 Evaluating metabolism A61B5/083 takes precedence
• CPC Class Codes: A61B 5/6849 in combination with a needle set
• CPC Class Codes: A61B 5/7275 Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
• CPC Class Codes: A61B 5/742 using visual displays A61B5/339 takes precedence
• CPC Class Codes: A61B 5/746 Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms alarms per se G08B
• CPC Class Codes: A61B 5/7475 User input or interface means, e.g. keyboard, pointing device, joystick
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 20/40 relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• CPC Class Codes: G16H 40/67 for remote operation

Abstract

Methods and system to provide glycemic control and therapy management based on monitored glucose data, and current and/or target Hb1AC levels are provided.

Claims

1. A method, comprising:

receiving mean glucose value information of a patient based on a predetermined time period;

receiving a current HbA1C level of the patient and a target HbA1C level of the patient;

determining a correlation between the received mean glucose value information and the retrieved current and target HbA1C levels;

updating the target HbA1C level based on the determined correlation; and

determining one or more parameters associated with the physiological condition of the patient based on the updated target HbA1C level.

2. The method of claim 1 wherein receiving mean glucose value information includes:

receiving monitored glucose level information over the predetermined time period; and

applying a weighting function to the received monitored glucose level information.

3. The method of claim 2 wherein the weighting function is based on a time of day information associated with the received monitored glucose level information.

4. The method of claim 2 wherein the weighting function is based on a time period associated with the received monitored glucose level information.

5. The method of claim 1 wherein updating the target HbA1C level includes:

receiving one or more patient specific parameters; and

applying the received one or more patient specific parameters to the determined correlation between the received mean glucose value information and the received current HbA1C level.

6. The method of claim 5 wherein the one or more patient specific parameters includes an age of the patient, a history of hypoglycemia, an activity level of the patient, a medication intake information of the patient, or a risk associated with high or low blood glucose levels of the patient.

7. The method of claim 1 wherein the determined correlation between the received mean glucose value information and the received current HbA1C level includes a rate of glycation of the patient.

8. The method of claim 1 wherein the predetermined time period includes one of approximately 30 days, approximately 45 days, or approximately 90 days.

9. The method of claim 1 wherein determining one or more parameters associated with the physiological condition of the patient includes one or more of providing modification to current alarm settings, providing modification to current target threshold settings related to the monitored analyte levels, or providing a modification to a medication intake level.

10. The method of claim 1 including storing one or more of the mean glucose value information, the received current or target HbA1C level, the determined correlation between the received mean glucose value information and the current HbA1C level, and the updated target HbA1C level.

11. An apparatus, comprising:

a communication interface;

one or more processors operatively coupled to the communication interface; and

a memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to receive mean glucose value information of a patient based on a predetermined time period, receive a current HbA1C level of the patient and a target HbA1C level of the patient, determine a correlation between the received mean glucose value information and the retrieved current and target HbA1C levels, update the target HbA1C level based on the determined correlation, and to determine one or more parameters associated with the physiological condition of the patient based on the updated target HbA1C level.

12. The apparatus of claim 11 wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to receive monitored glucose level information over the predetermined time period, to apply a weighting function to the received monitored glucose level information.

13. The apparatus of claim 12 wherein the weighting function is based on a time of day information associated with the received monitored glucose level information.

14. The apparatus of claim 12 wherein the weighting function is based on a time period associated with the received monitored glucose level information.

15. The apparatus of claim 11 wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to receive one or more patient specific parameters, and to apply the received one or more patient specific parameters to the determined correlation between the received mean glucose value information and the received current HbA1C level.

16. The apparatus of claim 15 wherein the one or more patient specific parameters includes an age of the patient, a history of hypoglycemia, an activity level of the patient, a medication intake information of the patient, or a risk associated with high or low blood glucose levels of the patient.

17. The apparatus of claim 11 wherein the determined correlation between the received mean glucose value information and the received current HbA1C level includes a rate of glycation of the patient.

18. The apparatus of claim 11 wherein the predetermined time period includes one of approximately 30 days, approximately 45 days, or approximately 90 days.

19. The apparatus of claim 11 wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to provide a modification to current alarm settings, provide modification to current target threshold settings related to the monitored analyte levels, or provide modification to a medication intake level.

20. The apparatus of claim 11 wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to store one or more of the mean glucose value information, the received current or target HbA1C level, the determined correlation between the received mean glucose value information and the HbA1C level, and the updated target HbA1C level.