UTILIZATION OF HYPERTENSION/HYPERCARDIA-PREVENTING EFFECT OF D-ALLOSE

• US 20090305999A1
• Filed: 08/31/2006
• Published: 12/10/2009
• Est. Priority Date: 08/31/2005
• Status: Active Grant

• Current Assignee: Matsutani Chemical industry Co,. Ltd., National University Corporation Kagawa University
• Original Assignee: Fushimi Pharmaceutical Co., Ltd., National University Corporation Kagawa University
• Inventors: Kimura, Shoji, Izumori, Ken, Tokuda, Masaaki
• Granted Patent: US 8,440,619 B2
• Time in Patent Office: Days
• US Class Current: 514/24
• CPC Class Codes: A23K 20/163 Sugars; Polysaccharides
• CPC Class Codes: A23L 33/10 using additives addition of substantially indigestible substances A23L33/21
• CPC Class Codes: A61K 31/7004 Monosaccharides having only carbon, hydrogen and oxygen atoms
• CPC Class Codes: A61P 9/00 Drugs for disorders of the cardiovascular system
• CPC Class Codes: A61P 9/12 Antihypertensives

Abstract

The object is to provide a novel application of D-allose (e.g., use for prevention of hypertension or hypercardia). Thus, disclosed is a composition for preventing the increase in blood pressure which comprises D-allose as an active ingredient; or a composition containing D-allose and/or a derivative thereof, preferably in an amount of 0.1 to 50% by weight. Preferably, the composition is in a form selected from the group consisting of a food additive, a food material, a beverage/food, a health beverage/food, a pharmaceutical and a feeding stuff which can be used for the prevention and treatment of a cardiovascular system disorder (e.g., hypertension, hypercardia). The increase in blood pressure may be caused by salt-sensitive hypertension. Also disclosed is use of D-allose for preventing the increase in blood pressure (excluding medical practices).

Claims

1. A composition for suppressing the increase of blood pressure, the composition containing D-allose as the active ingredient.

2. A composition for suppressing the increase of blood pressure according to claim 1, where the composition is in blend with D-allose and/or a derivative thereof.

3. A composition for suppressing the increase of blood pressure according to claim 1, where D-allose and/or a derivative thereof is blended to a content of 0.1 to 50% by weight in the composition.

4. A composition for suppressing the increase of blood pressure according to claim 1, where the composition is in a form selected from the group consisting of food additives, food materials, foods and drinks, health foods and drinks, pharmaceutical products and feeds in blend with D-allose and/or a derivative thereof as the active ingredient.

5. A composition for suppressing the increase of blood pressure according to claim 4, where the composition is in a form selected from the group consisting of food additives, food materials, foods and drinks, health foods and drinks, pharmaceutical products and feeds in blend with D-allose and/or a derivative thereof as the active ingredient, and which can be used for the prevention and therapeutic treatment of the onset of hypertension and/or the onset of cardiovascular diseases such as hypercardia.

6. A composition for suppressing the increase of blood pressure according to claim 1, where the increase of blood pressure is due to salt-sensitive hypertension.

7. A method for using D-allose for suppressing the increase of blood pressure (excluding the use for clinical practice).

8. A method for using D-allose according to claim 7, where the D-allose is D-allose, and/or a derivative thereof, and/or a composition in blend with D-allose and/or a derivative thereof.

9. A method for using D-allose according to claim 8, where in case that D-allose is a composition in blend with D-allose and/or a derivative thereof, the composition is in a form selected from the group consisting of food additives, food materials, foods and drinks, health foods and drinks, pharmaceutical products and feeds (excluding the use thereof for clinical practice).

10. A method for using D-allose according to claim 9, where the composition is in a form selected from the group consisting of food additives, food materials, foods and drinks, health foods and drinks, pharmaceutical products and feeds in blend with D-allose and/or a derivative thereof as the active ingredient, and which can be used for the prevention and therapeutic treatment of the onset of hypertension and/or the onset of cardiovascular diseases such as hypercardia (excluding the use thereof for clinical practice).

11. A method for using D-allose according to claim 9, where D-allose and/or a derivative thereof is blended to a content of 0.1 to 50% by weight in the composition (excluding the use thereof for clinical practice).

12. A method for using D-allose according to claim 7, where the increase of blood pressure is due to salt-sensitive hypertension (excluding the use thereof for clinical practice).