Assembly For Placing A Prosthetic Valve In A Duct In The Body

• US 20100036485A1
• Filed: 10/14/2009
• Published: 02/11/2010
• Est. Priority Date: 07/04/2001
• Status: Active Grant

• Current Assignee: Medtronic CV Luxembourg SARL (Medtronic Plc)
• Original Assignee: Medtronic Corevalve LLC (Medtronic Plc)
• Inventors: SEGUIN, Jacques
• Granted Patent: US 8,002,826 B2
• Time in Patent Office: Days
• US Class Current: 623/2.370
• CPC Class Codes: A61F 2/2403 with pivoting rigid closure members check valves with hinged closure members in general F16K15/03
• CPC Class Codes: A61F 2/2418 Scaffolds therefor, e.g. support stents
• CPC Class Codes: A61F 2220/0008 Fixation appliances for connecting prostheses to the body
• CPC Class Codes: A61F 2220/0016 with sharp anchoring protrusions, e.g. barbs, pins, spikes
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2250/006 modular

Abstract

The present invention is an assembly comprising a prosthetic valve to be implanted; a radially expandable stent comprising at least one zone intended to be expanded to allow the stent, in the expanded state, to bear against the wall of the body duct to be fitted with the valve, this bearing making it possible to immobilize this stent with respect to this wall; and means for mounting the valve with respect to the stent, making it possible to connect the valve to the stent in such a way that the placement of the stent allows the valve to be mounted in the body duct, and expansion means such as a balloon catheter being provided to trigger expansion of the stent at the implantation site. According to the invention, the valve and the stent are designed in such a way that, at the moment when the stent is expanded, the valve is situated outside the zone or zones of the stent that are subjected to said expansion means. The invention thus consists in separating the valve and said zone or zones to be expanded, so that the expansion of the stent can be effected with an expansion force suitable for perfect anchoring of this stent in the wall of the body duct to be fitted with the valve, and without any risk of destruction or damage of the valve.

Claims

1. A prosthetic valve assembly comprising:

an implantable prosthetic cardiac valve configured to permit blood flow in a first

direction and to inhibit blood flow in a second direction opposite to the first direction; and

a radially expandable annular support comprising a first inflatable peripheral chamber and a second inflatable peripheral chamber, wherein the first and second inflatable peripheral chambers are each configured to bear against a wall of a native body lumen when in an inflated stated, and wherein the annular support has a central lumen for permitting blood flow therethrough when the annular support is in an expanded position,

wherein the valve is mounted on the annular support, and wherein the valve assembly is configured to delivered by catheterization.

2. The assembly of claim 1, wherein the second inflatable chamber is configured to bear against the wall of the aorta proximal to a native valvular ring when in its inflated state.

3. The assembly of claim 1, wherein the first inflatable chamber is configured to bear against the wall of a ventricle proximal to a native valvular ring when in its inflated state.

4. The assembly of claim 1, wherein the first inflatable chamber is configured to bear against the native valvular ring.

5. The assembly of claim 1, wherein the second inflatable chamber is configured to bear against the native valvular ring.

6. The assembly of claim 1, wherein the annular support is formed generally in an hourglass shape.

7. The assembly of claim 1, wherein the annular support is formed at least partially of a biocompatible polymer.

8. The assembly of claim 7, wherein the first and second inflatable chambers are formed of a biocompatible polymer.

9. The assembly of claim 1, wherein the first and second inflatable chambers are configured to prevent leakage between the annular support and the native valvular ring.

10. The assembly of claim 2, wherein the second inflatable chamber is configured such that it is below the coronary ostia and does not obstruct the coronary arteries when in the inflated state.

11. The assembly of claim 1, wherein, when the annular support is in the expanded position, the valve is substantially within the native valvular ring.

12. The assembly of claim 1, wherein the annular support has a different diameter at the location of the first inflatable chamber than at the location of the second inflatable chamber when the annular support is in the expanded position.

13. The assembly of claim 12, wherein the annular support has a larger diameter at the location of the first inflatable chamber than at the location of the second inflatable chamber when the annular support is in the expanded position.

14. A prosthetic valve assembly comprising:

a prosthetic cardiac valve configured to replace the function of a natural cardiac valve; and

a radially expandable tubular support having a distal inflatable chamber and a proximal inflatable chamber connected thereto, wherein the distal inflatable chamber is configured to bear against a wall of an aorta in an inflated state, and wherein the proximal inflatable chamber is configured to bear against a wall of a ventricle in an inflated stated,

wherein the prosthetic cardiac valve is mounted on the tubular support, and wherein the valve assembly is configured to delivered by catheterization.

15. The assembly of claim 14, wherein the tubular support has a different diameter at the location of the proximal inflatable chamber than at the location of the distal inflatable chamber when the tubular support is in an expanded position.

16. The assembly of claim 15, wherein the tubular support has a larger diameter at the location of the proximal inflatable chamber than at the location of the distal inflatable chamber when the tubular support is in the expanded position.

17. The assembly of claim 14, wherein the distal inflatable chamber is configured such that it is below the coronary ostia and does not obstruct the coronary arteries when in the inflated state.

18. The assembly of claim 14, wherein the distal and proximal inflatable chambers are configured to prevent leakage between the tubular support and a native valvular ring.

19. The assembly of claim 14, wherein, when the tubular support is in an expanded position, the valve is substantially within a native cardiac valvular ring.