Modified nucleosides and nucleotides and uses thereof
2 Assignments
0 Petitions
Accused Products
Abstract
The invention is directed to modified guanine-containing nucleosides and nucleotides and uses thereof. More specifically, the invention relates to modified fluorescently labelled guanine-containing nucleosides and nucleotides which exhibit enhanced fluorophore intensity by virtue of reduced quenching effects.
2 Citations
30 Claims
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1-17. -17. (canceled)
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18. A modified nucleotide or nucleoside comprising a guanine base or a 7-deazaguanine base attached to a fluorophore through a cleavable linking group, wherein said linking group comprises a spacer group of formula —
- ((CH2)2O)n— and
n is an integer between 2 and 50. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30)
- ((CH2)2O)n— and
Specification