Intelligent medical device system for personalized medicine applications

• US 20100069888A1
• Filed: 08/07/2009
• Published: 03/18/2010
• Est. Priority Date: 08/08/2008
• Status: Active Grant

• Current Assignee: Neal Solomon
• Original Assignee: Neal Solomon
• Inventors: Solomon, Neal
• Granted Patent: US 8,617,873 B2
• Time in Patent Office: Days
• US Class Current: 604/890.100
• CPC Class Codes: A61B 2562/028 Microscale sensors, e.g. electromechanical sensors [MEMS]
• CPC Class Codes: A61B 5/00 Measuring for diagnostic purposes radiation diagnosis A61B6/00; diagnosis by ultrasonic, sonic or infrasonic waves A61B8/00; Identification of persons
• CPC Class Codes: A61B 5/4076 Diagnosing or monitoring particular conditions of the nervous system A61B5/4821, A61B5/4824 take precedence
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/415 the glands, e.g. tonsils, adenoids or thymus
• CPC Class Codes: A61B 5/416 the spleen
• CPC Class Codes: A61B 5/418 lymph vessels, ducts or nodes
• CPC Class Codes: A61B 5/4227 endocrine glands, i.e. thyroid, adrenals, hypothalamic, pituitary
• CPC Class Codes: A61B 5/4839 combined with drug delivery
• CPC Class Codes: A61N 1/36114 Cardiac control, e.g. by vagal stimulation stimulating the heart A61N1/362
• CPC Class Codes: B82Y 15/00 Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
• CPC Class Codes: G16H 10/40 for data related to laboratory analysis, e.g. patient specimen analysis
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders

Abstract

The system presents applications of personalized medicine with intelligent medical devices (iMDs) and customizes therapies to complex problems involving neurological, cardiovascular, cancer, immunological and endocrinological diseases.

Claims

1. A system for operation of a medical device for diagnostics, analysis and therapeutics for treatment of vascular diseases, comprising:

a set of layers of medical device components;

a set of compartments for storage of chemicals and biologicals;

a set of microfluidic components, including tubes, valves and gates;

a lab-on-a-chip (LOC) component in a diagnostic module;

a system on a chip (SoC);

wherein the medical device components include a set of compartments for combining chemicals and biologicals on at least one of a set of layers;

wherein the medical device diagnostics process includes obtaining cell, DNA, RNA and protein samples from the patient and analyzing the samples in the LOC;

wherein the LOC analysis data are forwarded to the SoC for modeling of the pathology;

wherein solution options are generated by the model;

wherein the medical device components are activated after obtaining data from a medical device model for therapeutic recommendations;

wherein the medical device components are coordinated to release specific chemicals and biologicals from compartments on at least one of a set of layers through the microfluidic components in specific measured doses according to the model recommendations;

wherein the chemicals and biologicals are combined in a chamber of the medical device module in one of a set of layers; and

wherein the resulting therapeutic combination is transmitted to a cell site in a patient for cerebrovascular, blood clot, arteriosclerosis, hemophilia, anemia and thrombocytopenia disorders.

2. A system for operation of a medical device for diagnostics, analysis and therapeutics for treatment of neoplasties, comprising:

a set of layers of medical device components;

a set of compartments for storage of chemicals and biologicals;

a set of microfluidic components, including tubes, valves and gates;

a lab-on-a-chip (LOC) component in a diagnostic module;

a system on a chip (SoC);

wherein the medical device components include a set of compartments for combining chemicals and biologicals on at least one of a set of layers;

wherein the medical device diagnostics process includes obtaining cell, DNA, RNA and protein samples from the patient and analyzing the samples in the LOC;

wherein the LOC analysis data are forwarded to the SoC for modeling of the pathology;

wherein solution options are generated by the model;

wherein the medical device components are activated after obtaining data from a medical device model for therapeutic recommendations;

wherein the medical device components are coordinated to release specific chemicals and biologicals from compartments on at least one of a set of layers through the microfluidic components in specific measured doses according to the model recommendations;

wherein the chemicals and biologicals are combined in a chamber of the medical device module in one of a set of layers; and

wherein the therapies are applied to abnormal cells.

3. A system for operation of a medical device for diagnostics, analysis and therapeutics for treatment of immunological diseases, comprising:

a set of layers of medical device components;

a set of compartments for storage of chemicals and biologicals;

a set of microfluidic components, including tubes, valves and gates;

a lab-on-a-chip (LOC) component in a diagnostic module;

a system on a chip (SoC);

wherein the medical device components include a set of compartments for combining chemicals and biologicals on at least one of a set of layers;

wherein the medical device diagnostics process includes obtaining cell, DNA, RNA and protein samples from the patient and analyzing the samples in the LOC;

wherein the LOC analysis data are forwarded to the SoC for modeling of the pathology;

wherein solution options are generated by the model;

wherein the medical device components are activated after obtaining data from a medical device model for therapeutic recommendations;

wherein the medical device components are coordinated to release specific chemicals and biologicals from compartments on at least one of a set of layers through the microfluidic components in specific measured doses according to the model recommendations;

wherein the chemicals and biologicals are combined in a chamber of the medical device module in one of a set of layers; and

wherein the therapies are applied to the cells of the human immune system.