PARTICLE-CONTAINING MEMBRANE AND PARTICULATE ELECTRODE FOR ANALYTE SENSORS

  • US 20100076283A1
  • Filed: 09/17/2009
  • Published: 03/25/2010
  • Est. Priority Date: 09/19/2008
  • Status: Active Grant
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First Claim
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1. An analyte detection system for continuous in vivo detection of an analyte, the system comprising:

  • a continuous analyte sensor comprising a working electrode configured for implantation in a host, wherein the working electrode comprises an electroactive surface, the continuous analyte sensor further comprising a membrane located over the working electrode, wherein the membrane comprises an enzyme domain and a particle-containing domain, wherein the particle-containing domain comprises a conductive component dispersed in a non-conductive component, wherein the conductive component comprises a plurality of conductive particles, wherein the particle-containing domain is located more distal to the electroactive surface than the enzyme domain, and wherein the particle-containing domain is configured to electrochemically react with at least one interfering species; and

    sensor electronics configured to generate a signal associated with an analyte in the host.

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