METHOD FOR SETTING A BASAL RATE PROFILE FOR AN INSULIN PUMP

• US 20100082167A1
• Filed: 10/16/2009
• Published: 04/01/2010
• Est. Priority Date: 04/19/2007
• Status: Active Grant

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Disetronic Licensing Ag
• Inventors: Haueter, Ulrich, Vering, Thomas
• Granted Patent: US 8,560,131 B2
• Time in Patent Office: Days
• US Class Current: 700/282
• CPC Class Codes: A61M 2005/14208 with a programmable infusion control system, characterised by the infusion program
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: G16H 20/17 delivered via infusion or injection

Abstract

Methods for setting a basal rate profile for an insulin pump with an input unit and a calculation unit are disclosed. A number of interpolation nodes for the basal rate profile are defined by means of the input unit of the insulin pump. A continuous function with respect to the interpolation nodes, which images the interpolation nodes and any previously stored basal rates, is formed using the calculation unit of the insulin pump, and a temporal sequence of basal rates to be released by the insulin pump during specific time intervals is generated from the continuous function using the calculation unit of the insulin pump.

Claims

1. A method for setting a basal rate profile for an insulin pump with an input unit and a calculation unit, comprising:

defining a number of interpolation nodes for the basal rate profile by means of the input unit of the insulin pump, an interpolation node being defined by a start time of a basal rate release and a basal rate to be released associated with this start time or an absolute or relative amount of insulin to be released associated with this start time;

forming a continuous function with respect to the interpolation nodes by interpolation and/or approximation using the calculation unit of the insulin pump, said function imaging the interpolation nodes; and

generating a temporal sequence of basal rates to be released by the insulin pump during specific time intervals from the continuous function using the calculation unit of the insulin pump, the continuous function for generating the temporal sequence of basal rates using the calculation unit being discretized.

2. A method according to claim 1, wherein the continuous function images stored basal rates in addition to the interpolation nodes.

3. A method according to claim 1, wherein four to ten interpolation nodes are defined.

4. A method according to claim 1, wherein at least 24 basal rates are generated.

5. A method according to claim 1, wherein less than 24 basal rates are generated, the number of the generated basal rates being greater than the number of the defined interpolation nodes.

6. A method according to claim 1, wherein, temporally, the time interval associated with the first basal rate of the temporal sequence immediately follows the time interval associated with the last basal rate.

7. A method according to claim 1, wherein a number of sign changes of the derivative of the continuous function is determined by the calculation unit and a warning signal is generated in the case where the number of sign changes exceeds a predetermined limit value.

8. A method according to claim 7, wherein the predetermined limit value is five.

9. A method according to claim 1, further comprising comparing the defined interpolation nodes to at least one of predefined interpolation nodes and any previously stored basal rates of a stored basal rate profile.

10. A method according to claim 9, wherein the continuous function is formed only in the case where the defined interpolation nodes deviate by no more than a predefined value from at least one of the predefined interpolation nodes and the previously stored basal rates of the stored basal rate profile.

11. A method according to claim 10, wherein the predefined value is no more than 20 percent.

12. A method according to claim 10, wherein the continuous function images the defined interpolation nodes and the previously stored basal rates.

13. A method according to claim 1, wherein the defined interpolation nodes are compared to at least one of predefined interpolation nodes and stored basal rates, and a warning signal is generated in the case where the defined interpolation nodes deviate from at least one of the predefined interpolation nodes and the stored basal rates by more than a predefined value.

14. A method according to claim 13, wherein the deviation is by more than 20 percent.

15. A method for setting a basal rate profile for an insulin pump with an input unit and a calculation unit, comprising:

defining a number of interpolation nodes for the basal rate profile by means of the input unit of the insulin pump, an interpolation node being defined by a start time of a basal rate release and a basal rate to be released associated with this start time or an absolute or relative amount of insulin to be released associated with this start time;

comparing the defined interpolation nodes to predefined interpolation nodes and any previously stored basal rates of a stored basal rate profile;

generating a warning signal in the case where the defined interpolation nodes deviate from the predefined interpolation nodes and the previously stored basal rates by more than a predefined value;

forming, only in the case where the defined interpolation nodes deviate by no more than the predefined value from the predefined interpolation nodes and the previously stored basal rates, a continuous function with respect to the interpolation nodes by interpolation and/or approximation using the calculation unit of the insulin pump, said function imaging the defined interpolation nodes and the previously stored basal rates; and

generating a temporal sequence of basal rates to be released by the insulin pump during specific time intervals from the continuous function when formed by using the calculation unit of the insulin pump, the continuous function for generating the temporal sequence of basal rates using the calculation unit being discretized.

16. A method according to claim 15, wherein the predefined value is 20 percent.

17. A method according to claim 15, further comprising determining a number of sign changes of the derivative of the continuous function by using the calculation unit and generating a warning signal in the case where the number of sign changes exceeds a predetermined limit value.

18. A method according to claim 17, wherein the predetermined limit value is five.