METHOD AND APPARATUS FOR MAGNETIC INDUCTION THERAPY

• US 20100168501A1
• Filed: 07/23/2009
• Published: 07/01/2010
• Est. Priority Date: 10/02/2006
• Status: Abandoned Application

• Current Assignee: Emkinetics, Inc.
• Original Assignee: Emkinetics, Inc.
• Inventors: Hermanson, Christopher, Burnett, Daniel Rogers
• Application Number:
  US12/508,529
• Publication Number:
  US 20100168501A1
• Time in Patent Office: Days
• US Class Current: 600/13
• CPC Class Codes: A61N 1/0456 Specially adapted for transcutaneous electrical nerve stimulation [TENS]
• CPC Class Codes: A61N 1/0476 Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
• CPC Class Codes: A61N 1/0551 Spinal or peripheral nerve electrodes
• CPC Class Codes: A61N 1/36007 of urogenital or gastrointestinal organs, e.g. for incontinence control
• CPC Class Codes: A61N 1/36017 with leads or electrodes penetrating the skin
• CPC Class Codes: A61N 1/36021 for treatment of pain
• CPC Class Codes: A61N 1/36057 adapted for stimulating afferent nerves
• CPC Class Codes: A61N 1/3787 from an external energy source
• CPC Class Codes: A61N 2/004 specially adapted for a specific therapy
• CPC Class Codes: A61N 2/006 for magnetic stimulation of nerve tissue
• CPC Class Codes: A61N 2/02 using magnetic fields produced by coils, including single turn loops or electromagnets A61N2/12 takes precedence

Abstract

An energy emitting apparatus for providing a medical therapy includes one or more energy generators, a logic controller electrically connected to the one or more energy generators, and one or more sensors that are connected to the logic controller for detecting electric conduction in a target nerve. The energy generators produce energy focused on the target nerve upon receiving a signal from the logic controller, and the energy is varied by the logic controller according to an input provided by the one or more sensors. The energy emitting apparatus includes one or more conductive coils that produce a magnetic field focused on the target nerve upon receiving an electric current from the logic controller based on input provided by the sensors. The sensor may also include a microneedle array to detect electrical conduction or an energy emitting apparatus may include a microneedle array to produce or deliver energy, e.g., an electrical or magnetic stimulus or field.

Claims

1. An energy emitting system for providing a medical therapy comprising:

at least one conductive coil disposed within or along a housing, where the at least one coil is configured to generate a magnetic field focused on a target nerve in proximity to the at least one coil;

at least one sensor configured to detect electrical conduction in the target nerve or muscle stimulation, wherein the sensor is comprised of a microneedle array attachable to a skin surface in proximity to a target nerve or muscle; and

a controller coupled to said at least one conductive coil and in communication with said at least one sensor.

2. The system of claim 1, wherein the magnetic field generated by said at least one conductive coil is varied based on the electrical conduction or muscle stimulation detected by said at least one sensor to ensure adequate therapeutic stimulation.

3. The system of claim 1, wherein the microneedle array is arrayed over a housing.

4. The system of claim 3, wherein the housing is comprised of a patch having at least one electrode and said microneedle array extends from a first surface of the electrode.

5. The system of claim 4, wherein the patch comprises a positive, negative and control electrode, each electrode comprising a microneedle array extending therefrom.

6. The system of claim 4, wherein the microneedle array is etched from a surface of the electrode.

7. The system of claim 1, wherein said microneedle array comprises at least one microneedle comprising an electrically conductive material such that it can transmit an electrical signal to an overlying electrode.

8. The system of claim 7, wherein said microneedle comprises metal, silicon, biocompatible polymers, titanium, silver, or suture material.

9. The system of claim 1, wherein said microneedle array comprises at least one microneedle coated with an electrically conductive material such that it can transmit an electrical signal to an overlying electrode.

10. The system of claim 1, wherein said microneedle array comprises at least one microneedle comprising a distal tip and a bulb extending from said distal tip to provide for anchoring of said microneedle into a subject'"'"'s skin.

11. The system of claim 1, wherein said microneedle array comprises at least one microneedle having a diameter in the range of about 1 to 100 microns.

12. The system of claim 11, wherein a diameter of said microneedle is in the range of about 10 to 30 microns.

13. The system of claim 1, wherein said microneedle array comprises at least one microneedle having a length in the range of about 1 to 100 microns.

14. The system of claim 13, wherein a length of said microneedle is in the range of about 100 to 150 microns.

15. The system of claim 1, further comprising an electrode needle coupled to said controller and having an end insertable into a subject'"'"'s body in proximity to a stimulation site, wherein said needle is inductively coupled to said at least one conductive coil.

16. The system of claim 15, wherein said at least one conductive coil is positioned distal to said stimulation site such that upon activation of said controller a current traverses the stimulation site by passing from said at least one conductive coil to said percutaneous electrode needle.

17. The system of claim 16, further comprising at least one conductive microneedle patch positioned distal to said stimulation site and coupled to the controller such that upon activation of said controller a current traverses the stimulation site by passing from said at least one conductive microneedle patch and said at least one conductive coil to said electrode needle.

18. An energy emitting system for providing a medical therapy comprising:

at least one conductive coil disposed within or along a housing, where the at least one coil is configured to generate a magnetic field focused on a target nerve in proximity to the at least one coil;

at least one sensor configured to detect electrical conduction in the target nerve or muscle stimulation, wherein the sensor is comprised of at least one microneedle comprising an electrically conductive material such that it can transmit an electrical signal to an overlying electrode and a distal tip having a bulb extending from said distal tip to provide for anchoring of said microneedle into a subject'"'"'s skin; and

a controller coupled to said at least one conductive coil and in communication with said at least one sensor.

19. An energy emitting system for providing a medical therapy comprising:

at least one microneedle patch comprised of a microneedle array deposited on a surface of at least one electrode, where said at least one microneedle patch is configured to generate an electrical or magnetic stimulus focused on a target nerve in proximity to the at least one conductive microneedle patch; and

a controller coupled to said at least one microneedle patch.

20. The system of claim 19, further comprising at least one sensor configured to detect the electrical conduction in the target nerve or muscle stimulation and attachable to a skin surface in proximity to a target nerve or muscle.

21. The system of claim 20, wherein the electrical or magnetic stimulus generated by said at least one microneedle patch is varied according to the electrical conduction or muscle stimulation detected by said at least one sensor to ensure adequate therapeutic stimulation.

22. The system of claim 19, wherein the microneedle array is etched from a surface of the electrode.

23. The system of claim 19, wherein said microneedle patch comprises at least one microneedle comprising an electrically conductive material such that it can transmit an electrical signal to an overlying electrode.

24. The system of claim 23, wherein said microneedle comprises metal, silicon, biocompatible polymers, titanium, silver, or suture material.

25. The system of claim 19, wherein said sensor is comprised of at least one microneedle array.

26. The system of claim 19, wherein said microneedle array comprises at least one microneedle comprising a distal tip and a bulb extending from said distal tip to provide for anchoring of said microneedle into a subject'"'"'s skin.

27. The system of claim 19, wherein said microneedle array comprises at least one microneedle having a diameter in the range of about 1 to 100 microns.

28. The system of claim 27, wherein a diameter of said microneedle is in the range of about 10 to 30 microns.

29. The system of claim 19, wherein said microneedle array comprises at least one microneedle having a length in the range of about 1 to 150 microns.

30. The system of claim 29, wherein a length of said microneedle is in the range of about 100 to 150 microns.

31. The system of claim 19, further comprising an electrode needle coupled to said controller and having an end insertable into a subject'"'"'s body in proximity to a stimulation site, wherein said needle is inductively coupled to said at least one conductive microneedle patch.

32. The system of claim 31, wherein said at least one microneedle patch is positioned distal to said stimulation site such that upon activation of said controller a current traverses the stimulation site by passing from said at least one microneedle patch to said electrode needle.

33. The system of claim 32, further comprising at least one conductive coil positioned distal to said stimulation site and coupled to said controller such that upon activation of said controller a current traverses the stimulation site by passing from said at least one microneedle patch and said at least one conductive coil to said electrode needle.

34. An energy emitting system for providing a medical therapy comprising:

at least one conductive microneedle patch comprised of a microneedle array deposited on a surface of at least one electrode, wherein said microneedle array comprises an electrically conductive material such that it can transmit an electrical signal to an overlying electrode and a distal tip having a bulb extending from said distal tip to provide for anchoring of said microneedle into a subject'"'"'s skin, said microneedle patch configured to deliver an electrical or magnetic stimulus to a target nerve in proximity to the at least one conductive microneedle patch;

at least one sensor configured to detect electrical conduction in the target nerve or muscle stimulation and attachable to a skin surface in proximity to a target nerve or muscle; and

a controller coupled to said at least one conductive microneedle patch and in communication with said at least one sensor.

35. An energy emitting system for providing a medical therapy comprising:

at least one conductive coil disposed within or along a housing, where the at least one coil is configured to generate a magnetic field focused on a target nerve in proximity to the at least one coil;

an electrode needle having an end insertable into a subject'"'"'s body in proximity to a stimulation site, wherein said needle is inductively coupled to said at least one conductive coil; and

a controller coupled to said at least one conductive coil and said electrode needle.

36. The system of claim 35, wherein said at least one conductive coil is positioned distal to said stimulation site such that upon activation of said controller a current traverses the stimulation site by passing from said at least one conductive coil to said electrode needle.

37. The system of claim 35, further comprising at least one sensor in communication with said controller and configured to detect electrical conduction in the target nerve or muscle stimulation and attachable to a skin surface in proximity to a target nerve or muscle, wherein the magnetic field generated by said at least one conductive coil is varied based on the muscle stimulation or electrical conduction detected by said at least one sensor to ensure adequate therapeutic stimulation.

38. A method of treating a subject with urinary incontinence comprising:

positioning a first portion of a subject'"'"'s body, the subject exhibiting symptoms associated with urinary incontinence, relative to an energy emitting device such that a tibial nerve within the first portion of the body is in proximity to at least one energy generator disposed within or along the energy emitting device;

passing a current through the at least one energy generator to produce a magnetic field or electrical stimulus focused on the tibial nerve;

stimulating a nerve that innervates the pelvic floor of the subject via stimulation of the tibial nerve with the magnetic field or electrical stimulus; and

reducing symptoms associated with urinary incontinence.

39. The method of claim 38, wherein the energy generator comprises a conductive coil for generating a magnetic field.

40. The method of claim 39, wherein positioning comprises placing a foot, ankle, or leg relative to at least one conductive coil disposed within or along a housing.

41. The method of claim 39, wherein positioning comprises placing a popliteal fossa relative to at least one conductive coil disposed within or along a housing.

42. The method of claim 38, wherein the energy generator comprises a microneedle patch for producing a magnetic field or electrical stimulus.

43. The method of claim 38, wherein a nerve that innervates the pelvic floor comprises the pudendal nerve or sacral plexus.

44. The method of claim 38, wherein symptoms associated with urinary incontinence comprise urinary leakage, loss of bladder control and the inability to control urinary function.

45. The method of claim 38, further comprising detecting electrical conduction through the tibial nerve or corresponding muscle stimulation via at least one sensor positioned along a second portion of the body.

46. The method of claim 45, wherein the sensor comprises a microneedle array.

47. The method of claim 45, wherein the sensor is positioned in proximity to the tibial nerve, over a muscle innervated by the tibial nerve, or over the popliteal fossa.

48. The method of claim 45, further comprising adjusting the current via a controller in communication with the energy generator according to a signal received from the sensor indicative of the nerve conduction.

49. The method of claim 48, wherein adjusting comprises adjusting amplitude, frequency direction of a magnetic field, or firing sequence of the energy generator.

50. The method of claim 48, wherein adjusting comprises adjusting a position of the at least one coil relative to the first portion of the subject'"'"'s body to re-focus the magnetic field on the tibial nerve.

51. The method of claim 48, wherein adjusting comprises adjusting a position of the microneedle patch relative to the first portion of the subject'"'"'s body to re-focus the electrical or magnetic stimulus on the tibial nerve.

52. The method of claim 48, wherein adjusting comprises varying the current according to a muscular response in the patient.

53. The method of claim 39, wherein the conductive coil is operated at about 10 to 20 hertz to generate a magnetic field of about 0.25 to 1.5 tesla for a duration of about 30 minutes per day.

54. A method of treating a subject with urinary incontinence comprising:

positioning a first portion of a subject'"'"'s body, the subject exhibiting symptoms associated with urinary incontinence, relative to a housing such that a posterior tibial nerve within the first portion of the body is in proximity to at least one conductive coil disposed within or along the housing;

passing a current through the at least one conductive coil to produce a magnetic field focused on the posterior tibial nerve;

detecting electrical conduction of the posterior tibial nerve via at least one microneedle array positioned along a second portion of the body;

receiving a signal from the microneedle array indicative of the electrical conduction;

adjusting the current via a controller in communication with the conductive coil according to the signal received from the microneedle array; and

reducing symptoms associated with urinary incontinence.