IN VIVO RFID CHIP

• US 20100171596A1
• Filed: 12/31/2009
• Published: 07/08/2010
• Est. Priority Date: 12/31/2008
• Status: Active Grant

• Current Assignee: Regents of the University of California (University of California)
• Original Assignee: Regents of the University of California (University of California)
• Inventors: Rutherglen, Christopher M., Burke, Peter J.
• Granted Patent: US 8,830,037 B2
• Time in Patent Office: Days
• US Class Current: 340/10.400
• CPC Class Codes: G06K 19/0717 the sensor being capable of sensing environmental conditions such as temperature history or pressure
• CPC Class Codes: G06K 19/07749 the record carrier being capable of non-contact communication, e.g. constructional details of the antenna of a non-contact smart card
• CPC Class Codes: H04Q 2209/47 using RFID associated with sensors
• CPC Class Codes: H04Q 2209/88 Providing power supply at the sub-station
• CPC Class Codes: H04Q 9/00 Arrangements in telecontrol or telemetry systems for selectively calling a substation from a main station, in which substation desired apparatus is selected for applying a control signal thereto or for obtaining measured values therefrom

Abstract

An in vivo RFID chip implanted in a patient'"'"'s body, comprising an integrated antenna formed on the chip, and a CMOS-compatible circuitry adapted for biosensing and transmitting information out of the patient'"'"'s body. In preferred embodiments, the CMOS-compatible circuitry is adapted to sense a chemical and/or physical quantity from a local environment in the patient'"'"'s body and to control drug release from the drug reservoirs based on the quantity sensed.

Claims

1. An in vivo RFID chip implanted in a patient'"'"'s body, comprising

an integrated antenna formed on the chip, and

a CMOS-compatible circuitry adapted for biosensing and transmitting information out of the patient'"'"'s body.

2. The chip of claim 1, wherein the antenna is integrated with a rectifier circuit and supplies power to the chip by converting AC power into a DC voltage.

3. The chip of claim 1 further comprising drug reservoirs coupled to the CMOS-compatible circuitry.

4. The chip of claim 3, wherein the CMOS-compatible circuitry is adapted to sense a chemical and/or physical quantity from a local environment in the patient'"'"'s body and to control drug release from the drug reservoirs based on the quantity sensed.

5. The chip of claim 1, wherein the chip is powered by a power source from outside the patient'"'"'s body.

6. The chip of claim 1, wherein the chip is adapted to electrically stimulate biological function in the patient'"'"'s body.

7. The chip of claim 1, wherein neither the length nor the width of the chip exceeds 100 μ

m

8. The chip of claim 1, wherein the antenna comprises at least one nanotube.

9. The chip of claim 1, wherein the CMOS-compatible circuitry is integrated with a plurality of sensors.

10. A method of interrogating biological systems, comprising the steps of:

implanting in a patient'"'"'s body an RFID chip having an integrated antenna formed on the chip and a CMOS-compatible circuitry;

sensing a physical and/or chemical quantity through a plurality of sensors integrated in the CMOS-compatible circuitry;

converting the physical and/or chemical quantity into a measurable signal; and

transmitting the signal out of the body via the integrated antenna on the RFID chip.