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Methods For Immobilizing Anti-Thrombogenic Material Onto A Medical Device Or Into A Coating Thereon

  • US 20100173065A1
  • Filed: 01/06/2010
  • Published: 07/08/2010
  • Est. Priority Date: 07/30/2001
  • Status: Active Grant
First Claim
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1. A method for immobilizing an anti-thrombogenic material into a coating posited on a surface of an implantable medical device within the mammalian body, comprising:

  • preparing a base coat mixture for application to the surface of the medical device;

    polymerizing the base coat mixture to form a base coat layer on the medical device;

    performing a reaction between the base coat layer and excess amine-terminated polyethylene glycol;

    rinsing the base coat layer with water; and

    performing a reaction between the anti-thrombogenic material and amine-terminated polyethylene glycol on the surface of the medical device.

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