Computerized Determination of Insulin Pump Therapy Parameters Using Real Time and Retrospective Data Processing

• US 20100198314A1
• Filed: 01/30/2009
• Published: 08/05/2010
• Est. Priority Date: 01/30/2009
• Status: Active Grant

• Current Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Abbott Diabetes Care Incorporated (Abbott Laboratories Incorporated)
• Inventors: Wei, Charles
• Granted Patent: US 8,560,082 B2
• Time in Patent Office: Days
• US Class Current: 607/67
• CPC Class Codes: A61M 2205/35 Communication
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 5/142 Pressure infusion, e.g. using pumps
• CPC Class Codes: A61M 5/172 electrical or electronic A61M5/16804, A61M5/16831 take precedence
• CPC Class Codes: G16H 20/17 delivered via infusion or injection
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 40/67 for remote operation
• CPC Class Codes: G16Z 99/00 Subject matter not provided for in other main groups of this subclass

Abstract

Methods and devices for providing computerized adjustment to therapy parameters using real time and retrospective data processing is provided. Embodiments include receiving a respective data set from an infusion device and an analyte monitoring device for a predetermined time duration, user notification and reminder of the predetermined time duration, time synchronizing the received respective data set, detecting one or more marked data from the one or more respective data set received, establishing one or more filtering criteria to filter of retrospective or historical data based on certain condition, performing automated data analysis based on the detected one or more marked data or the data achieving certain predetermined condition to generate a modification to a therapy profile, generating and modifying rules for profile modification, and providing the generated modification to the therapy profile for reporting and transmission.

Claims

1. A method, comprising:

receiving a respective data set from an infusion device and an analyte monitoring device for a predetermined time duration;

time synchronizing the received respective data set;

detecting one or more marked data from the one or more respective data set received;

performing automated data analysis based on the detected one or more marked data to generate a modification to a therapy profile; and

providing the generated modification to the therapy profile.

2. The method of claim 1 wherein the data set from the infusion device includes an executed medication delivery profile associated with the predetermined time duration.

3. The method of claim 1 wherein the infusion device is configured to notify the user that the predetermined time duration is in effect.

4. The method of claim 1 including performing automated data analysis based on detection of the occurrence of a preset number of events and/or conditions in the retrospective data set to generate a modification to a therapy profile.

5. The method of claim 4 including providing user formulation tools to modify one or more rules or guidelines for therapy modification.

6. The method of claim 1 wherein the data set from the analyte monitoring device includes monitored analyte level associated with the predetermined time duration.

7. The method of claim 1 wherein the analyte monitoring device is configured to notify the user that the predetermined time duration is in effect.

8. The method of claim 1 wherein time synchronizing the received respective data set includes aligning the time of event occurrence information for associated events of each data set based on a common time base.

9. The method of claim 1 wherein the detected one or more marked data includes an indication of a meal event, exercise event, drug ingestion event, health state event, hypoglycemic event, hyperglycemic event, rate of change of analyte level exceeding a predetermined threshold level, therapy compliance information, missed analyte sensor calibration event, missed meal bolus event, frequency alarm event, and frequency of alert event.

10. The method of claim 1 wherein performing the automated data analysis includes refining an executed therapy profile based at least in part in the data processing associated with the marked data and related information.

11. The method of claim 1 wherein performing the automated data analysis includes refining an executed therapy profile based at least in part in the data processing associated with the pre-defined filter criteria of unmarked data.

12. The method of claim 1 wherein the automated data analysis is initiated in response to the detection of the marked data.

13. The method of claim 1 wherein the automated data analysis is initiated in response to the data achieving a preset number of pre-defined events or conditions.

14. The method of claim 1 wherein the therapy profile includes insulin therapy profile, glucose alarm settings, target blood glucose profile, carbohydrate ratio profile or insulin sensitivity profile.

15. The method of claim 1 including transmitting the generated modification to the therapy profile in response to a received confirmation.

16. The method of claim 1 including generating or modifying one or more rules for generating therapy profile modification.

17. An apparatus, comprising:

a data communication interface;

one or more processors operatively coupled to the data communication interface; and

a memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to receive a respective data set from an infusion device and an analyte monitoring device for a predetermined time duration, time synchronize the received respective data set, detect one or more marked data from the one or more respective data set received, perform automated data analysis based on the detected one or more marked data to generate a modification to a therapy profile, and provide the generated modification to the therapy profile.

18. The apparatus of claim 17 wherein the data set from the infusion device includes an executed medication delivery profile associated with the predetermined time duration.

19. The apparatus of claim 17 wherein the memory for storing instructions which, when executed by the one or more processors causes the one or more processors to issue one or more notification to perform or prohibit performance of one or more user based events during the predetermined time period.

20. The apparatus of claim 17 wherein the data set from the analyte monitoring device includes monitored analyte level associated with the predetermined time duration.

21. The apparatus of claim 17 wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to align the time information of each data set based on a common time base.

22. The apparatus of claim 17 wherein the detected one or more marked data includes an indication of a meal event, exercise event, drug ingestion event, health state event, hypoglycemic event, hyperglycemic event, rate of change of analyte level exceeding a predetermined threshold level, therapy compliance information, missed analyte sensor calibration event, missed meal bolus event, frequency alarm event, and frequency of alert event.

23. The apparatus of claim 17 wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to refine an executed therapy profile based at least in part in the data processing associated with the marked data and related information.

24. The apparatus of claim 17 wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to refine an executed therapy profile based at least in part in the data processing associated with the pre-defined filter criteria of unmarked data.

25. The apparatus of claim 17 wherein the automated data analysis is initiated in response to the detection of the marked data.

26. The apparatus of claim 17 wherein the therapy profile includes insulin therapy profile, glucose alarm settings, target blood glucose profile, carbohydrate ratio profile, or insulin sensitivity profile.

27. The apparatus of claim 17 wherein the memory for storing instructions which, when executed by the one or more processors, causes the one or more processors to transmit the generated modification to the therapy profile in response to a received confirmation.

28. The apparatus of claim 17 wherein the memory for storing instructions which, when executive by one of more processors, causes the one or more processors to update one or more rules for generating therapy profile modification.

29. One or more storage devices having processor readable code embodied thereon, said processor readable code for programming one or more processors to fine tune therapy profile, comprising:

receiving a respective data set from an infusion device and an analyte monitoring device for a predetermined time duration;

time synchronizing the received respective data set;

detecting one or more marked data from the one or more respective data set received;

performing automated data analysis based on the detected one or more marked data to generate a modification to a therapy profile; and

providing the generated modification to the therapy profile.