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IL-1 Binding Proteins

  • US 20100221179A1
  • Filed: 01/29/2010
  • Published: 09/02/2010
  • Est. Priority Date: 01/29/2009
  • Status: Active Grant
First Claim
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1. A binding protein comprising a variable heavy chain polypeptide comprising having an amino acid sequence selected from the group consisting of SEQ ID No. 37, SEQ ID No. 38, SEQ ID No. 39, SEQ ID No. 40, SEQ ID No. 48, SEQ ID No. 50, SEQ ID No. 52, and SEQ ID No. 54;

  • and a variable light chain polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID No. 41, SEQ ID No. 42, SEQ ID No. 43, SEQ ID No. 44, SEQ ID No. 45, SEQ ID No. 46, SEQ ID No. 47, SEQ ID No. 49, SEQ ID No. 51, SEQ ID No. 53, and SEQ ID No. 55;

    wherein said binding protein is capable of binding human IL-1α

    .

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