BENZAMIDE DERIVATIVES USEFUL AS HISTONE DEACETYLASE INHIBITORS
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Abstract
The invention concerns a compound of the formula (I)
wherein Ring A is heterocyclyl; m is 0-4 and each R1 is a group such as hydroxy, halo, trifluoromethyl and cyano; R2 is halo and n is 0-2; and each R4 is a group such as hydroxy, halo, trifluoromethyl and cyano; p is 0-4; and R3 is amino or hydroxy;
or pharmaceutically-acceptable salts or in-vivo-hydrolysable ester or amide thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical condions mediated by histone deacetylase.
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17 Claims
- 1. A compound of the formula (I):
Specification