METAL VASCULAR APERTURE CLOSURE DEVICE

• US 20110009901A1
• Filed: 07/13/2009
• Published: 01/13/2011
• Est. Priority Date: 07/13/2009
• Status: Active Grant

• Current Assignee: Teleflex Life Sciences LLC (Teleflex Incorporated)
• Original Assignee: Vascular Solutions Incorporated
• Inventors: Welch, Jeff, Root, Howard, Holman, Tom
• Granted Patent: US 8,252,022 B2
• Time in Patent Office: Days
• US Class Current: 606/213
• CPC Class Codes: A61B 17/0057 Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009
• CPC Class Codes: A61B 2017/00659 located only on one side of the opening

Abstract

A closure device to be inserted at least partially through a blood vessel wall aperture in a blood vessel wall. The closure device includes at least two parts, an internal part and an external part. The internal part is adapted to be extended at least partially through the blood vessel wall aperture and into the lumen to at least partially block the blood vessel wall aperture. Each of the internal part and the external part consists essentially of a metal that biodegrades within a living being in a period of time that permits biological repair of the blood vessel wall in and around the blood vessel aperture.

Claims

1. A closure device to be inserted at least partially through a blood vessel wall aperture in a blood vessel wall, the blood vessel having a lumen, the closure device comprising:

at least two parts, including an internal part and an external part, the internal part being adapted to be extended at least partially through the blood vessel wall aperture and into the lumen to at least partially block the blood vessel wall aperture, each of the internal part and the external part consisting essentially of a metal that biodegrades within a living being in a period of time that permits biological repair of the blood vessel wall in and around the blood vessel wall and at least the external part being movable relative to the internal part.

2. The closure device as claimed in claim 1, wherein the metal is magnesium.

3. The closure device as claimed in claim 2, wherein the magnesium has a purity in a range from about 90.0 percent to about 99.99 percent.

4. The closure device as claimed in claim 2, wherein the magnesium is about 99.80 percent pure.

5. The closure device as claimed in claim 1, wherein at least one of the two parts has had its surface topography altered whereby biodegradation of at least part the closure device is facilitated.

6. The closure device as claimed in claim 5, wherein the surface topography has been altered by particulate blasting whereby biodegradation of at least part the closure device is facilitated.

7. The closure device as claimed in claim 1, further comprising a buffer whereby pH near at least part of the closure device is affected and whereby biodegradation of at least part the closure device is facilitated.

8. The closure device as claimed in claim 2, wherein the magnesium is alloyed with another metal.

9. The closure device as claimed in claim 8, wherein the other metal comprises iron.

10. The closure device as claimed in claim 8, wherein the other metal comprises manganese.

11. A method of substantially blocking fluid leakage from an aperture in a blood vessel wall of a blood vessel, the blood vessel having a lumen, the method comprising:

inserting a device at least partially into the blood vessel aperture, the device having at least two parts, including an internal part and an external part, each of the internal part and the external part consisting essentially of a metal that biodegrades within a living being in a period of time that permits biological repair of the blood vessel wall in and around the blood vessel aperture;

extending the internal part at least partially through the blood vessel wall aperture and into the lumen to at least partially block the blood vessel wall aperture; and

moving the external part relative and the internal part relative to each other by tensioning a tensioning member between the internal part within the blood vessel lumen and the external part outside of the blood vessel wall.

12. The method as claimed in claim 11, further comprising selecting the metal to be magnesium.

13. The method as claimed in claim 11, further comprising selecting the magnesium to have a purity in a range from about 90.0 percent to about 99.99 percent.

14. The method as claimed in claim 11, further comprising selecting at the magnesium to have a purity of about 99.80 percent.

15. The method as claimed in claim 11, further comprising selecting at least one of the internal part and the external;

part to have a surface topography that is altered by particulate blasting whereby biodegradation of at least part the closure device is facilitated.

16. The method as claimed in claim 11, further comprising selecting at least one of the internal part and the external;

part to have a surface topography that is altered by particulate blasting with a metallic oxide wherein the metal in the metallic oxide is a different metal that the metal from which the parts are formed whereby biodegradation of at least part the closure device is facilitated.

17. The method as claimed in claim 11, further comprising selecting the metal to be magnesium alloyed with another metal.

18. The method as claimed in claim 17, further comprising selecting the other metal to comprise iron.

19. The method as claimed in claim 17, further comprising selecting the other metal to comprise manganese.