VALVE UNIT AND REACTION APPARATUS HAVING THE SAME

• US 20110126918A1
• Filed: 12/27/2010
• Published: 06/02/2011
• Est. Priority Date: 04/04/2006
• Status: Active Grant

• Current Assignee: Precision Biosensor Inc.
• Original Assignee: Samsung Electronics Co. Ltd.
• Inventors: PARK, Jong-myeon, HONG, Sung-woo, CHO, Yoon-kyuong, LEE, Jeong-gun, LEE, Beom-seok
• Granted Patent: US 8,499,793 B2
• Time in Patent Office: Days
• US Class Current: 137/341
• CPC Class Codes: B01L 2300/0803 Disc shape
• CPC Class Codes: B01L 2300/1861 using radiation
• CPC Class Codes: B01L 2400/0409 centrifugal forces
• CPC Class Codes: B01L 2400/0677 phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
• CPC Class Codes: B01L 3/502738 characterised by integrated valves microvalves F16K99/0001
• CPC Class Codes: F16K 2099/0084 Chemistry or biology, e.g. "lab-on-a-chip" technology
• CPC Class Codes: F16K 99/0001 Microvalves microdevices B81B1/00; manufacture or treatment of devices or systems in or on a substrate B81C1/00; microfluidic structures B01L3/5027; micropumps F04B19/006
• CPC Class Codes: F16K 99/0019 Valves using a microdroplet or microbubble as the valve member
• CPC Class Codes: F16K 99/0032 using phase transition or influencing viscosity
• CPC Class Codes: F16K 99/0034 Operating means specially adapted for microvalves
• CPC Class Codes: F16K 99/004 using radiation
• CPC Class Codes: Y10T 137/1827 With heater for destructible or fusible element
• CPC Class Codes: Y10T 137/2196 Acoustical or thermal energy
• CPC Class Codes: Y10T 137/6606 With electric heating element
• CPC Class Codes: Y10T 137/7755 Reactor surface normal to flow

Abstract

Provided are a valve unit and a reaction apparatus having the valve unit. The valve unit includes a phase transition material, which melts and expands upon an application of the electromagnetic waves to the valve filler, and the valve filler is directed into the channel through the connection passage and closes the channel. The valve unit also includes heat generation particles, which are dispersed in the phase transition material and generate heat upon an application of electromagnetic wave energy.

Claims

1. A valve unit comprising:

a valve filler which includes a phase transition material and a plurality of heat generation particles;

a chamber to receive the valve filler;

a fluid channel which is connected to the chamber; and

an external energy source which comprises a laser beam source irradiating a laser beam,

wherein the heat generation particles are dispersed in the phase transition material and generate heat upon an application of electromagnetic wave energy of the laser beam from the laser beam source, and

wherein the phase transition material melts and expands upon an application of heat which is generated by the heat generation materials, and the valve filler is directed into the channel and closes the channel.

2. The valve unit of claim 1, wherein the laser beam source includes a laser diode.

3. The valve unit of claim 1, wherein the laser beam emitted from the laser beam source is a pulse electromagnetic wave having an energy of at least 1 mJ/pulse.

4. The valve unit of claim 1, wherein the laser beam emitted from the laser beam source is a continuous wave electromagnetic wave having an output of at least 10 mW.

5. The valve unit of claim 1, wherein the laser beam emitted from the laser beam source has a wavelength in the range of 750 to 1300 nm.

6. The valve unit of claim 1, wherein the heat generation particles have an average diameter in the range of 1 nm to 100 μ

m.

7. The valve unit of claim 6, wherein the heat generation particles are dispersed in a hydrophobic carrier oil.

8. The valve unit of claim 1, wherein the heat generation particles include a ferromagnetic material or a metal oxide.

9. The valve unit of claim 8, wherein the metal oxide is at least one selected from the group consisting of Al₂O₃, TiO₂, Ta₂O₃, Fe₂O₃, Fe₂O₄, and HfO₂.

10. The valve unit of claim 1, wherein the heat generation particles are in the form of a quantum dot or a magnetic bead.

11. The valve unit of claim 1, wherein the heat generation particles are formed of a polymer.

12. The valve unit of claim 11, wherein the heat generation particles are magnetic beads and the magnetic beads are formed of a magnetic material selected from the group consisting of Fe, Ni, Cr, and an oxide thereof.

13. The valve unit of claim 12, wherein the magnetic beads has a core formed from the magnetic material and further comprises an outer hydrophobic layer formed on the magnetic material core.

14. The valve unit of claim 1, wherein the phase-transition material is at least one selected from the group consisting of wax, a gel, and a thermoplastic resin.

15. The valve unit of claim 14, wherein the wax is at least one selected from the group consisting of paraffin wax, microcrystalline wax, synthetic wax, and natural wax.

16. The valve unit of claim 14, wherein the gel is formed of at least one material selected from the group consisting of polyacrylamide, polyacrylates, polymethacrylates, and polyvinylamides.

17. The valve unit of claim 14, wherein the thermoplastic resin is at least one selected from the group consisting of a cyclic olefin copolymer, a polymethylmethacrylate, a polycarbonate, a polystyrene, a polyoxymethylene, a perfluoralkoxy, a polyvinylchloride, a polypropylene, a polyethylene terephthalate, a polyetheretherketone, a polyamide, a polysulfone, and a polyvinylidene fluoride.

18. A valve unit comprising:

a substrate;

a channel formed in the substrate defining a path through which a fluid flows;

a plug formed in the channel to block the path of the fluid in the channel when the plug is in a solid state at a room temperature, the plug including a phase change material and a plurality of heat-dissipating particles dispersed in the phase change material; and

an external energy source which irradiates the plug with electromagnetic energy,

wherein, when the plug is irradiated with the electromagnetic energy, the plurality of fine heat-dissipating particles dissipate heat and the phase change material become molten opening the path to allow the fluid to flow.