MICRONEEDLE COMPONENT ASSEMBLY FOR DRUG DELIVERY DEVICE

• US 20110172609A1
• Filed: 01/08/2010
• Published: 07/14/2011
• Est. Priority Date: 01/08/2010
• Status: Abandoned Application

• Current Assignee: FluGen, Inc., Ratio, Inc.
• Original Assignee: FluGen, Inc., Ratio, Inc.
• Inventors: Smith, Garrick D.S., Moga, Benjamin J., Chase, Kent
• Application Number:
  US12/684,823
• Publication Number:
  US 20110172609A1
• Time in Patent Office: Days
• US Class Current: 604/272
• CPC Class Codes: A61M 2037/0023 Drug applicators using microneedles
• CPC Class Codes: A61M 2037/003 having a lumen
• CPC Class Codes: A61M 2037/0053 Methods for producing microneedles
• CPC Class Codes: A61M 37/0015 by using microneedles
• CPC Class Codes: A61M 5/14224 Diaphragm type
• CPC Class Codes: A61M 5/14248 of the skin patch type
• CPC Class Codes: A61M 5/14586 pressurised by means of a flexible diaphragm
• CPC Class Codes: A61M 5/14593 the diaphragm being actuated by fluid pressure
• CPC Class Codes: Y10T 29/49826 Assembling or joining

Abstract

A device for delivering a drug to a subject is provided. The device includes a drug reservoir, a conduit coupled to the drug reservoir and a microneedle component. The microneedle component includes a body, an engagement structure coupling the microneedle component to the conduit, a hollow microneedle extending from the body, and a handling feature located on the body. The microneedle component is configured to be releasably coupled to an assembly tool via the handling feature during assembly of the device.

Claims

1. A device for delivering a drug to a subject, the device comprising:

a drug reservoir;

a conduit coupled to the drug reservoir; and

a microneedle component comprising;

a body;

an engagement structure coupling the microneedle component to the conduit;

a hollow microneedle extending from the body; and

a handling feature located on the body;

wherein the microneedle component is configured to be releasably coupled to an assembly tool via the handling feature during assembly of the device.

2. The device of claim 1, wherein the handling feature is configured such that the microneedle component is aligned relative to the assembly tool in a predetermined manner after coupling to the assembly tool.

3. The device of claim 1, wherein the handling feature includes a recess formed in the body of the microneedle component, and further wherein sidewalls of the recess are configured to be engaged by the assembly tool to couple the microneedle component to the assembly tool.

4. The device of claim 3, wherein the recess is non-circular.

5. The device of claim 4, wherein the recess is triangular, and further wherein the engagement structure includes a first tab, a second tab, and a third tab, and the conduit includes a first opening, a second opening, and a third opening, wherein the microneedle component is coupled to the conduit via engagement between the first tab and the first opening, engagement between the second tab and the second opening, and engagement between the third tab and the third opening.

6. The device of claim 5, wherein the engagement between the tabs and the openings is a snap-fit engagement.

7. The device of claim 5, wherein each corner of the triangular recess is aligned with one of the tabs.

8. The device of claim 7, wherein the body of the microneedle component includes a sidewall and has a generally circular cross-sectional area, and further wherein the tabs extend from the outer surface of the sidewall.

9. The device of claim 8, wherein the tabs are evenly spaced around the periphery of the sidewall.

10. A microneedle component of a drug delivery device, comprising:

a bottom wall having a lower surface;

a sidewall coupled to the bottom wall;

a microneedle extending from the lower surface of the bottom wall; and

a robotic handling feature formed in the lower surface of the bottom wall, the robotic handling feature configured to be releasably coupled to a robotic assembly tool during assembly of the drug delivery device.

11. The microneedle component of claim 10, wherein the robotic handling feature is configured such that the microneedle component is aligned relative to the robotic assembly tool in a predetermined manner after being coupled to the robotic assembly tool.

12. The microneedle component of claim 11, wherein the sidewall includes an inner surface and the bottom wall includes an upper surface, wherein the inner surface of the sidewall and the upper surface of the bottom wall define a central recess facing an upper end of the microneedle component, and further wherein the microneedle includes a central channel in fluid communication with the central recess.

13. The microneedle component of claim 12, wherein the robotic handling feature includes a recess formed in the lower surface of the bottom wall, the recess of the robotic handling feature facing a lower end of the microneedle component.

14. The microneedle component of claim 13, further comprising a plurality of tabs extending from an outer surface of the sidewall, the plurality of tabs configured to couple the microneedle component to the drug delivery device.

15. A method of manufacturing a drug delivery device, the method comprising:

providing a microneedle component having a robotic handling feature;

providing a drug reservoir;

providing a conduit coupled to the drug reservoir;

coupling the microneedle component to a robotic transfer device via engagement between the robotic handling feature and the robotic transfer device; and

coupling the microneedle component to the conduit with the robotic transfer device.

16. The method of claim 15, further comprising:

coupling the microneedle component to a second robotic transfer device via engagement between the robotic handling feature and the second robotic transfer device;

removing the microneedle component from a molding machine with the second robotic transfer device;

placing the microneedle component into a shipping container using the second robotic transfer device; and

removing the microneedle component from the shipping container with the robotic transfer device.

17. The method of claim 15, further comprising providing a housing and coupling the drug reservoir, conduit and microneedle component to the housing.

18. The method of claim 15, wherein the coupling the microneedle component step includes positioning the microneedle component within a portion of the conduit.

19. The method of claim 15, wherein the robotic handling feature is configured such that the microneedle component is aligned relative to the robotic transfer device in a predetermined manner after being coupled to the robotic transfer device.

20. The method of claim 19, wherein the coupling of the microneedle component to the conduit with the robotic transfer device is based on the predetermined alignment of the microneedle component relative to the robotic transfer device.