METHODS AND APPARATUS FOR THE PLANNING AND DELIVERY OF RADIATION TREATMENTS
First Claim
1. A method for planning delivery of radiation dose to a target region within a subject, the method comprising:
- iteratively optimizing a simulated dose distribution relative to a set of one or more optimization goals over a preceding plurality of control points, the preceding plurality of control points located along a preceding trajectory which characterizes relative movement between a radiation source and a subject; and
upon reaching one or more preceding optimization termination conditions, iteratively optimizing a simulated dose distribution relative to the set of one or more optimization goals over an increased plurality of control points, the increased plurality of control points located along at least one subsequent trajectory which characterizes relative movement between the radiation source and the subject and the increased plurality of control points comprising a larger number of control points than the preceding plurality of control points.
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Accused Products
Abstract
Methods and apparatus are provided for planning and delivering radiation treatments by modalities which involve moving a radiation source along a trajectory relative to a subject while delivering radiation to the subject. In some embodiments the radiation source is moved continuously along the trajectory while in some embodiments the radiation source is moved intermittently. Some embodiments involve the optimization of the radiation delivery plan to meet various optimization goals while meeting a number of constraints. For each of a number of control points along a trajectory, a radiation delivery plan may comprise: a set of motion axes parameters, a set of beam shape parameters and a beam intensity.
102 Citations
22 Claims
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1. A method for planning delivery of radiation dose to a target region within a subject, the method comprising:
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iteratively optimizing a simulated dose distribution relative to a set of one or more optimization goals over a preceding plurality of control points, the preceding plurality of control points located along a preceding trajectory which characterizes relative movement between a radiation source and a subject; and upon reaching one or more preceding optimization termination conditions, iteratively optimizing a simulated dose distribution relative to the set of one or more optimization goals over an increased plurality of control points, the increased plurality of control points located along at least one subsequent trajectory which characterizes relative movement between the radiation source and the subject and the increased plurality of control points comprising a larger number of control points than the preceding plurality of control points. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
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17. A method for providing software for use in planning delivery of radiation dose to a target region within a subject, the method comprising:
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implementing a network-accessible location offering the software for download from a computer server system, the computer server system comprising one or more computer-readable storage media having a computer-readable software program embodied thereon for use in planning delivery of radiation dose to a target region within a subject, the computer-readable software program comprising instructions for; iteratively optimizing a simulated dose distribution relative to a set of one of more optimization goals over a preceding plurality of control points, the preceding plurality of control points located along a preceding trajectory which characterizes relative movement between a radiation source and a subject; and upon reaching one or more preceding optimization termination conditions, iteratively optimizing a simulated dose distribution relative to the set of one or more optimization goals over an increased plurality of control points, the increased plurality of control points located along at least one subsequent trajectory which characterizes relative movement between the radiation source and the subject and the increased plurality of control points comprising a larger number of control points than the preceding plurality of control points; transmitting, by the computer server system and over the network, the computer-readable software program to a client computer-readable storage medium.
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18. A computer program product having computer-readable instructions embodied thereon, the instructions, when executed by a processor cause the processor to execute a method for planning delivery of radiation dose to a target region within a subject, the method comprising:
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iteratively optimizing a simulated dose distribution relative to a set of one of more optimization goals over a preceding plurality of control points, the preceding plurality of control points located along a preceding trajectory which characterizes relative movement between a radiation source and a subject; and upon reaching one or more preceding optimization termination conditions, iteratively optimizing a simulated dose distribution relative to the set of one or more optimization goals over an increased plurality of control points, the increased plurality of control points located along at least one subsequent trajectory which characterizes relative movement between the radiation source and the subject and the increased plurality of control points comprising a larger number of control points than the preceding plurality of control points.
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19. A method for planning delivery of radiation dose to a target region within a subject, the method comprising:
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iteratively optimizing a simulated dose distribution relative to a set of one of more optimization goals over a preceding plurality of control points; wherein, prior to iteratively optimizing the simulated dose distribution over the preceding plurality of control points, the preceding plurality of control points are located along a preceding trajectory which characterizes relative movement between a radiation source and a subject; and wherein iteratively optimizing the simulated dose distribution over the preceding plurality of control points comprises optimizing spatial locations of one or more of the preceding plurality of preceding control points to thereby determine an optimized preceding trajectory. - View Dependent Claims (20, 21, 22)
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Specification