ARTERIOSCLEROSIS EVALUATING APPARATUS

• US 20110208073A1
• Filed: 02/28/2011
• Published: 08/25/2011
• Est. Priority Date: 09/01/2008
• Status: Active Grant

• Current Assignee: Doshisha Company Limited, Murata Manufacturing Co Limited
• Original Assignee: Doshisha Company Limited, Murata Manufacturing Co Limited
• Inventors: FURUYA, Mio, SAITO, Masashi, WATANABE, Yoshiaki, MATSUKAWA, Mami, ASADA, Takaaki
• Granted Patent: US 8,696,580 B2
• Time in Patent Office: Days
• US Class Current: 600/508
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/0285 Measuring or recording phase velocity of blood waves
• CPC Class Codes: A61B 5/6822 Neck
• CPC Class Codes: A61B 8/06 Measuring blood flow measuring volume flow in general G01F, e.g. G01F1/66, G01F1/72; measuring speed of fluids in general G01P5/00

Abstract

The disclosed is an arteriosclerosis evaluating apparatus capable of easily separating pulse wave data detected at one measurement site into an incident wave and a reflected wave and capable of easily determining and evaluating the degree of arteriosclerosis. The pulse wave transmitted through an artery is detected at one site of a living body by a pulse wave detection device, and the detected pulse wave is fitted with a fitting function by a breakdown device so that the detected pulse wave can be broken down into an incident wave and a reflected wave. The degree of arteriosclerosis is evaluated from the amplitude intensities (i.e., peak intensities) of the incident wave and the reflected wave broken down from the pulse wave.

Claims

1. An arteriosclerosis evaluating apparatus comprising:

a pulse wave detection device adapted to detect a pulse wave transmitted through an artery at one point of a living body;

a breakdown device adapted to perform fitting of the pulse wave detected by the pulse wave detection device with a fitting function to break down the pulse wave into a plurality of developed waves; and

an evaluation device adapted to evaluate a degree of arteriosclerosis from amplitude intensities of the developed waves broken down from the pulse wave.

2. The arteriosclerosis evaluating apparatus according to claim 1, wherein the pulse wave detection device detects the pulse wave as a displacement signal.

3. The arteriosclerosis evaluating apparatus according to claim 1, wherein the fitting function is an exponential Gaussian function.

4. The arteriosclerosis evaluating apparatus according to claim 1, wherein the fitting function is a prepared model function.

5. The arteriosclerosis evaluating apparatus according to claim 4, wherein the prepared model function is an incident wave prepared by measuring blood flow velocities of subjects in every age group, by calculating an average blood flow velocity waveform by performing normalization of waveforms of the measured blood flow velocities to equalize time intervals between respective maximum amplitude intensities and respective notches of the waveforms and by estimating the incident wave by use of the average blood flow velocity waveform.

6. The arteriosclerosis evaluating apparatus according to claim 5, wherein the breakdown device is further adapted to fit the incident wave to a first wave of the pulse wave and to calculate a reflected wave by subtracting the incident wave from the pulse wave,

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensity of the reflected wave or a comparison of the incident wave and the reflected wave in amplitude intensity.

7. The arteriosclerosis evaluating apparatus according to claim 1,

wherein the breakdown device is further adapted to fit a first wave of the pulse wave with the fitting function to identify an incident wave, and to subtract the incident wave from the pulse wave to calculate a reflected wave, and

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensities of the incident wave and the reflected wave.

8. The arteriosclerosis evaluating apparatus according to claim 7,

wherein the breakdown device is further adapted to break down the reflected wave into a plurality of reflected waves by use of the fitting function;

and

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensity of the incident wave and the amplitude intensity of the first reflected wave of the plurality of reflected waves.

9. The arteriosclerosis evaluating apparatus according to claim 1, wherein the pulse wave detection device includes a piezoelectric transducer adapted to detect the pulse wave as a velocity signal.

10. The arteriosclerosis evaluating apparatus according to claim 9, wherein the pulse wave detection device further includes an integrator adapted to perform time integration of outputs from the piezoelectric transducer.

11. The arteriosclerosis evaluating apparatus according to claim 2, wherein the fitting function is an exponential Gaussian function.

12. The arteriosclerosis evaluating apparatus according to claim 2, wherein the fitting function is a prepared model function.

13. The arteriosclerosis evaluating apparatus according to claim 12, wherein the prepared model function is an incident wave prepared by measuring blood flow velocities of subjects in every age group, by calculating an average blood flow velocity waveform by performing normalization of waveforms of the measured blood flow velocities to equalize time intervals between respective maximum amplitude intensities and respective notches of the waveforms and by estimating the incident wave by use of the average blood flow velocity waveform.

14. The arteriosclerosis evaluating apparatus according to claim 13, wherein the breakdown device is further adapted to fit the incident wave to a first wave of the pulse wave and to calculate a reflected wave by subtracting the incident wave from the pulse wave,

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensity of the reflected wave or a comparison of the incident wave and the reflected wave in amplitude intensity.

15. The arteriosclerosis evaluating apparatus according to claim 2,

wherein the breakdown device is further adapted to fit a first wave of the pulse wave with the fitting function to identify an incident wave, and to subtract the incident wave from the pulse wave to calculate a reflected wave, and

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensities of the incident wave and the reflected wave.

16. The arteriosclerosis evaluating apparatus according to claim 3,

wherein the breakdown device is further adapted to fit a first wave of the pulse wave with the fitting function to identify an incident wave, and to subtract the incident wave from the pulse wave to calculate a reflected wave, and

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensities of the incident wave and the reflected wave.

17. The arteriosclerosis evaluating apparatus according to claim 4,

wherein the breakdown device is further adapted to fit a first wave of the pulse wave with the fitting function to identify an incident wave, and to subtract the incident wave from the pulse wave to calculate a reflected wave, and

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensities of the incident wave and the reflected wave.

18. The arteriosclerosis evaluating apparatus according to claim 15,

wherein the breakdown device is further adapted to break down the reflected wave into a plurality of reflected waves by use of the fitting function;

and

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensity of the incident wave and the amplitude intensity of the first reflected wave of the plurality of reflected waves.

19. The arteriosclerosis evaluating apparatus according to claim 16,

wherein the breakdown device is further adapted to break down the reflected wave into a plurality of reflected waves by use of the fitting function;

and

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensity of the incident wave and the amplitude intensity of the first reflected wave of the plurality of reflected waves.

20. The arteriosclerosis evaluating apparatus according to claim 17,

wherein the breakdown device is further adapted to break down the reflected wave into a plurality of reflected waves by use of the fitting function;

and

wherein the evaluation device evaluates the degree of arteriosclerosis from the amplitude intensity of the incident wave and the amplitude intensity of the first reflected wave of the plurality of reflected waves.