Preparation Method of Ferroferric Oxide Magnetic Nanospheres

• US 20110318261A1
• Filed: 12/31/2008
• Published: 12/29/2011
• Est. Priority Date: 12/31/2008
• Status: Active Grant

• Current Assignee: Xi'An Goldmag Nanobiotech Co., Ltd.
• Original Assignee: Xi'An Goldmag Nanobiotech Co., Ltd.
• Inventors: Peng, Mingli, Zhang, Caiquan, Cui, Yali, Chen, Chao, Zeng, Jinghui
• Granted Patent: US 8,409,544 B2
• Time in Patent Office: Days
• US Class Current: 423/632
• CPC Class Codes: B82Y 25/00 Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
• CPC Class Codes: B82Y 30/00 Nanotechnology for materials or surface science, e.g. nanocomposites
• CPC Class Codes: C01G 49/08 Ferroso-ferric oxide [Fe3O4]
• CPC Class Codes: C01P 2004/32 Spheres
• CPC Class Codes: C01P 2004/64 Nanometer sized, i.e. from 1-100 nanometer
• CPC Class Codes: C01P 2006/42 Magnetic properties
• CPC Class Codes: H01F 1/0045 Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use preparation of fullerenes in general C01B32/15

Abstract

Disclosed is a process of preparing magnetite nanoparticles, comprising the following steps: 1) preparing a ferric salt mixed system, wherein a soluble ferric salt is dissolved in glycol at ambient temperature, and then urea and polyethylene glycol are added and mixed homogeneously to obtain the trivalent iron salt mixed system, the mass ratio of glycol to the trivalent iron salt being 15:1 to 60:1, glycol to urea being 20:1 to 100:1, and glycol to polyethylene glycol being 20:1 to 100:1; 2) reacting, wherein the trivalent iron salt mixed system is transferred into a reaction autoclave, sealed and placed into a heating device to react at a temperature of 200 to 300° C. for 8 to 72 hours; and 3) washing, wherein after the reaction system is naturally cooled down to ambient temperature, the product is taken out, and washed with anhydrous ethanol and water in turn to obtain the magnetite nanoparticles. The soluble iron salt includes ferric chloride, ferric sulfate, ferric acetate and ferric nitrate. The obtained nanospheres exhibit a uniform distribution of the particle diameter with a good dispersity in water. The nanospheres have superparamagnetism, and their particle diameter can be controlled by varying the reaction time as desired.

Claims

1. A process of preparing magnetite nanoparticles, characterized in that it includes the following steps:

1) preparing a ferric salt mixed system, wherein a soluble ferric salt is dissolved in glycol at ambient temperature, and then urea and polyethylene glycol are added and mixed uniformly to obtain the ferric salt mixed system,

the mass ratio of glycol to the ferric salt being 15;

1 to 60;

1, glycol to urea being 20;

1 to 100;

1, and glycol to polyethylene glycol being 20;

1 to 100;

1;

2) reacting, wherein the ferric salt mixed system is transferred into a reaction autoclave, sealed and placed into a heating device to react at a temperature of 200 to 300°

C. for 8 to 72 hours; and

3) washing, wherein after the reaction system is naturally cooled down to ambient temperature, the product is taken out, and washed with anhydrous ethanol and water in turn to obtain the magnetite nanoparticles.

2. The process of preparing magnetite nanoparticles according to claim 1, characterized in that the soluble ferric salt includes ferric chloride, ferric sulfate, ferric acetate and ferric nitrate.

3. The process of preparing magnetite nanoparticles according to claim 1, characterized in that polyethylene glycol has a molecular weight between 400 and 20,000.

4. The process of preparing magnetite nanoparticles according to claim 2, characterized in that polyethylene glycol has a molecular weight between 400 and 20,000.