Automatic Generation of Patient-Specific Radiation Therapy Planning Parameters
First Claim
1. A method comprising:
- receiving by a data-processing system one or more data, wherein at least one of said data is based on a geometric characterization of one or more organs at risk proximate to a target volume of a patient P; and
generating by said data-processing system one or more radiation treatment planning parameters for said patient P based on said one or more data.
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Abstract
An apparatus and method for automatically generating radiation treatment planning parameters are disclosed. In accordance with the illustrative embodiment, a database is constructed that stores: (i) patient data and past treatment plans by expert human planners for these patients, and (ii) optimal treatment plans that are generated using multi-objective optimization and Pareto front search and that represent the best tradeoff opportunities of the patient case, and a predictive model (e.g., a neural network, a decision tree, a support vector machine [SVM], etc.) is then trained via a learning algorithm on a plurality of input/output mappings derived from the contents of the database. During training, the predictive model is trained to identify and infer patterns in the treatment plan data through a process of generalization. Once trained, the predictive model can then be used to automatically generate radiation treatment planning parameters for new patients.
64 Citations
20 Claims
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1. A method comprising:
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receiving by a data-processing system one or more data, wherein at least one of said data is based on a geometric characterization of one or more organs at risk proximate to a target volume of a patient P; and generating by said data-processing system one or more radiation treatment planning parameters for said patient P based on said one or more data. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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- 11. A method comprising training by a data-processing system a predictive model on a plurality of input-output mappings, wherein the output of each input-output mapping is based on a dose distribution and a dose volume histogram for a respective patient, and wherein the input of each input-output mapping comprises one or more data that are based on a geometric characterization of one or more organs at risk proximate to a target volume of the respective patient.
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19. A method comprising storing in a database, by a data-processing system:
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(a) one or more planning parameters of a first radiation treatment plan, wherein said first radiation treatment plan is for a first patient and is generated by one of; (i) an expert human planner, and (ii) a data-processing system using one or both of multi-objective optimization and pareto front search; (b) a first geometric characterization of a first non-empty set of organs at risk proximate to a first target volume of said first patient; (c) one or more planning parameters of a second radiation treatment plan, wherein said second radiation treatment plan is for a second patient and is generated by one of; (i) an expert human planner, and (ii) a data-processing system using one or both of multi-objective optimization and pareto front search; and (d) a second geometric characterization of a second non-empty set of organs at risk proximate to a second target volume of said second patient. - View Dependent Claims (20)
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Specification