POSTERIOR SEGMENT DRUG DELIVERY
First Claim
1. An implantable therapeutic device to treat an eye of a patient having a posterior chamber, the therapeutic device comprising:
- a rigid refillable reservoir;
a penetrable barrier coupled to the refillable reservoir, said barrier adapted to receive an injection of a therapeutic agent into the reservoir and to remain external to the posterior chamber; and
a rigid porous structure having a plurality of interconnecting channels, said rigid porous structure tuned to release therapeutic amounts of a therapeutic agent through said plurality of channels and into said posterior chamber for an extended time.
1 Assignment
0 Petitions
Accused Products
Abstract
A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side.
-
Citations
29 Claims
-
1. An implantable therapeutic device to treat an eye of a patient having a posterior chamber, the therapeutic device comprising:
-
a rigid refillable reservoir; a penetrable barrier coupled to the refillable reservoir, said barrier adapted to receive an injection of a therapeutic agent into the reservoir and to remain external to the posterior chamber; and a rigid porous structure having a plurality of interconnecting channels, said rigid porous structure tuned to release therapeutic amounts of a therapeutic agent through said plurality of channels and into said posterior chamber for an extended time. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
-
-
25. A therapeutic device to treat an eye of a patient, the eye having a posterior chamber, the therapeutic device comprising:
-
a rigid-walled reservoir having a volume; a rigid, porous structure having a plurality of intersecting channels, said porous structure and rigid-walled reservoir tuned to release a predetermined rate profile of a particular therapeutic agent through said plurality of channels and into the posterior chamber to treat the eye for an extended period of time; and a proximal portion comprising a retention structure and a penetrable barrier to introduce said therapeutic agent into said device without any need to explant the device during introduction of the therapeutic agent into the reservoir chamber. - View Dependent Claims (26, 27, 28, 29)
-
Specification