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METHODS FOR CONCOMITANT TREATMENT OF THEOPHYLLINE AND FEBUXOSTAT

  • US 20120065215A1
  • Filed: 11/14/2011
  • Published: 03/15/2012
  • Est. Priority Date: 09/10/2010
  • Status: Active Grant
First Claim
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1. A method of treating hyperuricemia in a patient in need of treatment thereof, the method comprising the steps of:

  • administering to a patient suffering from hyperuricemia and at least one second disease state, a therapeutically effective amount of at least one xanthine oxidoreductase inhibitor, wherein the subject is also receiving concomitant administration of theophylline to treat the at least one second disease state, andfurther wherein (i) the administration of the at least one xanthine oxidoreductase inhibitor to the patient does not result in theophylline toxicity to the patient; and

    (ii) administration of the theophylline is in an amount ranging from about 90% to about 110% of a manufacturer'"'"'s recommended theophylline dosage amount in the absence of administration of at least one xanthine oxidoreductase inhibitor.

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